Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes.
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Extracellular alkaline pH leads to increased metastatic potential of estrogen receptor silenced endocrine resistant breast cancer cellsThe spatial organization of proton and lactate transport in a rat brain tumorExpression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchangerUpregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H⁺ extrusion, cell migration and survival.Cell growth inhibition and apoptotic effects of a specific anti-RTFscFv antibody on prostate cancer, but not glioblastoma, cellsAutocrine regulation of glioma cell proliferation via pHe-sensitive K(+) channelsA hybrid cellular automaton model of clonal evolution in cancer: the emergence of the glycolytic phenotype.Expression and activity of carbonic anhydrase IX is associated with metabolic dysfunction in MDA-MB-231 breast cancer cellsThe human proton-coupled folate transporter: Biology and therapeutic applications to cancer.Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas.An acidic environment changes cyclin D1 localization and alters colony forming ability in gliomas.Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer questionEndogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer.HCO3(-)-independent pH regulation in astrocytes in situ is dominated by V-ATPase.Increased H⁺ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression.Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: a 31P/1H MRSI and quantitative magnetic resonance imaging studyGlioma-specific cation conductance regulates migration and cell cycle progressionPhysiology and pathophysiology of Na+/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood.Endosomal Na+/H+ exchanger NHE5 influences MET recycling and cell migration.Cation-coupled bicarbonate transportersDifferential gene expression profiles of gastric cancer cells established from primary tumour and malignant ascites2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.Glucose Uptake and Intracellular pH in a Mouse Model of Ductal Carcinoma In situ (DCIS) Suggests Metabolic Heterogeneity.Effect of NHE1 antisense gene transfection on the biological behavior of SGC-7901 human gastric carcinoma cellsCerebral microvascular endothelial cell Na/H exchange: evidence for the presence of NHE1 and NHE2 isoforms and regulation by arginine vasopressin.Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research.Involvement of tumor acidification in brain cancer pathophysiology.Role of pHi, and proton transporters in oncogene-driven neoplastic transformation.Systematic identification of genes involved in metabolic acid stress resistance in yeast and their potential as cancer targets.Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis.Role of Kir4.1 channels in growth control of glia.Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange.A unique modulator of endoplasmic reticulum stress-signalling pathways: the novel pharmacological properties of amiloride in glial cells.Stimulation of astrocyte Na+/H+ exchange activity in response to in vitro ischemia depends in part on activation of ERK1/2.Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice.Development and validation of chemical features-based proton-coupled folate transporter/activity and reduced folate carrier/activity models (pharmacophores).Sodium bicarbonate cotransporter NBCe2 gene variants increase sodium and bicarbonate transport in human renal proximal tubule cells.Tunable Stability of Imidazotetrazines Leads to a Potent Compound for GlioblastomaElevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomasBlockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy
P2860
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P2860
Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Malignant gliomas display alte ...... ith nontransformed astrocytes.
@en
type
label
Malignant gliomas display alte ...... ith nontransformed astrocytes.
@en
prefLabel
Malignant gliomas display alte ...... ith nontransformed astrocytes.
@en
P2093
P2860
P1476
Malignant gliomas display alte ...... ith nontransformed astrocytes.
@en
P2093
P2860
P304
P356
10.1152/AJPCELL.2000.278.4.C676
P577
2000-04-01T00:00:00Z