Invariant chain influences the immunological recognition of MHC class II molecules.
about
HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cellsMajor histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin LThe invariant chain is required for intracellular transport and function of major histocompatibility complex class II moleculesDefective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expressionA role for calnexin (IP90) in the assembly of class II MHC moleculesThe segment of invariant chain that is critical for association with major histocompatibility complex class II molecules contains the sequence of a peptide eluted from class II polypeptidesStable surface expression of invariant chain prevents peptide presentation by HLA-DR.Binding of an invariant-chain peptide, CLIP, to I-A major histocompatibility complex class II molecules.The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation.Efficient endosomal localization of major histocompatibility complex class II-invariant chain complexes requires multimerization of the invariant chain targeting sequence.Ii chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes.Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides.Enhanced antigen presentation in the absence of the invariant chain endosomal localization signal.The requirement for DM in class II-restricted antigen presentation and SDS-stable dimer formation is allele and species dependent.Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles.Invariant chain controls H2-M proteolysis in mouse splenocytes and dendritic cellsInvariant chain modulates HLA class II protein recycling and peptide presentation in nonprofessional antigen presenting cellsMR1 uses an endocytic pathway to activate mucosal-associated invariant T cellsThe cell biology of antigen processing.Invariant chain can function as a chaperone protein for class II major histocompatibility complex molecules.Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulationCholesterol lowering drug may influence cellular immune response by altering MHC II function.Distinct binding sites on HLA-DR for invariant chain and staphylococcal enterotoxins.Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex A alpha A beta dimers from the endoplasmic reticulum/cis-Golgi compartment.Transgenic mice with ectopic expression of alloantigenic MHC molecules--why are they so different and of how much help are they?Toward a Network Model of MHC Class II-Restricted Antigen Processing.An ion pair in class II major histocompatibility complex heterodimers critical for surface expression and peptide presentation.Sequence of rat cDNA clone pLR beta 112 coding for the RT1.D beta I chain.Introducing endogenous antigens into the major histocompatibility complex (MHC) class II presentation pathway. Both Ii mediated inhibition and enhancement of endogenous peptide/MHC class II presentation require the same Ii domains.pRB is required for interferon-gamma-induction of the MHC class II abeta gene.Epitope-specific enhancement of antigen presentation by invariant chain.Syk tyrosine kinase and B cell antigen receptor (BCR) immunoglobulin-alpha subunit determine BCR-mediated major histocompatibility complex class II-restricted antigen presentation.Common peptide epitope in mumps virus nucleocapsid protein and MHC class II-associated invariant chain.Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways.The antiphospholipid syndrome and SLE: is there a clue in the link between complement and coagulation?
P2860
Q24675139-69292040-FF1A-41F5-873B-5019FDF0A415Q24678337-42E830CB-6EDD-4B4B-8B7C-B57C9F4B776FQ28585584-28B7B8F9-3462-43B4-B959-711A618F824AQ28585705-D1097EEB-AD5D-4305-8707-FB7B5ECC3FB1Q28613001-A7F9DEB2-1EAC-401E-AB68-ED1605C74830Q28613064-E39C386E-7450-4F03-9A87-FD577305AE29Q33938149-6B885C6A-648C-4026-A94E-7982EB429778Q34871822-28E9D52A-4B96-4A3C-8CED-E476ABF73AF8Q36118069-D4877A33-7E74-4851-8968-C7A3E01BBF0AQ36235619-EE17EBC9-DD9A-4D0F-8235-8123E5EAAAF2Q36274077-E679A7F6-37F8-402E-B8C7-C69A884E8760Q36285397-1BDD31A2-3E3B-43C0-9AAB-042FA42D2542Q36362597-1359186A-0080-4BE3-9329-587B3853BDC0Q36364225-2FDB959C-4CE9-454F-9B74-5438E1A021AAQ36364770-76ACCA98-C14B-4914-92A1-A4C525BC1E90Q36368351-4A37DE27-33FC-4C7B-9AA4-F602E77C8C05Q36478578-BF54B1E8-AE84-474B-98E6-1074F185EE8BQ36640043-5AEA27E0-2A2D-4538-90ED-5E5E9087852AQ36707417-89B085CB-2F74-4A23-94BC-21E5F3814CD5Q36892768-60DA30B9-9581-410B-8BE1-7D03734F1DE2Q36949900-25DC6318-38B5-4C13-B99C-46BCEB0DE453Q37222694-8E6EC6A8-ED72-4E04-A894-29E65AE521DFQ37248357-2C04121A-FE14-4836-8AE3-BB11EE83231FQ37438792-8B0D4BF4-E81C-47EA-8EF6-023A330DCD84Q37449609-627449CB-ABA6-47BD-86D8-75B0FF67D735Q38174882-B138981B-7814-4985-838D-40D53E5E9ECAQ38291315-50FC65C5-F64C-4448-AE19-24146EDD271BQ40519130-A840834C-3082-4290-B066-D553B088733DQ40809420-61FA3784-6CFD-4BA8-BFDC-B13DBC3062EBQ40928341-CC6C1C0A-B404-4B8C-8ADD-097038A41E7BQ41937027-DBE3564E-DB6A-4BE5-A81D-1216D00BBDC6Q42972658-0058990D-1D3E-4E1D-9E39-44F270718548Q43889009-D614AB43-36FC-4215-9762-0460B751B2A8Q46424023-1EA43180-C2D2-452C-9D3B-67A37B28C086Q57254750-7A84415C-D7E8-4922-9353-0337E0E722BA
P2860
Invariant chain influences the immunological recognition of MHC class II molecules.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Invariant chain influences the immunological recognition of MHC class II molecules.
@en
type
label
Invariant chain influences the immunological recognition of MHC class II molecules.
@en
prefLabel
Invariant chain influences the immunological recognition of MHC class II molecules.
@en
P356
P1433
P1476
Invariant chain influences the immunological recognition of MHC class II molecules.
@en
P2093
P2888
P304
P356
10.1038/345172A0
P407
P577
1990-05-01T00:00:00Z
P6179
1008571384