Syk tyrosine kinase and B cell antigen receptor (BCR) immunoglobulin-alpha subunit determine BCR-mediated major histocompatibility complex class II-restricted antigen presentation.
about
Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tailLipid rafts and B cell signalingAutonomic nervous system and immune system interactionsDynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activationSyk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptorActin-binding protein 1 regulates B cell receptor-mediated antigen processing and presentation in response to B cell receptor activation.Intracellular traffic to compartments for MHC class II peptide loading: signals for endosomal and polarized sorting.Therapeutic targeting of Syk in autoimmune diabetesMonovalent ligation of the B cell receptor induces receptor activation but fails to promote antigen presentation.Immunotherapy of cancer by active vaccination: does allogeneic bone marrow transplantation after non-myeloablative conditioning provide a new option?Dysfunctional BLK in common variable immunodeficiency perturbs B-cell proliferation and ability to elicit antigen-specific CD4+ T-cell help.The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation.Independent trafficking of Ig-alpha/Ig-beta and mu-heavy chain is facilitated by dissociation of the B cell antigen receptor complexStudying MHC class II presentation of immobilized antigen by B lymphocytes.The transmembrane tyrosine of micro-heavy chain is required for BCR destabilization and entry of antigen into clathrin-coated vesicles.A mutation in Epstein-Barr virus LMP2A reveals a role for phospholipase D in B-Cell antigen receptor trafficking.BCR targeting of biotin-{alpha}-galactosylceramide leads to enhanced presentation on CD1d and requires transport of BCR to CD1d-containing endocytic compartments.The actin cytoskeleton is required for the trafficking of the B cell antigen receptor to the late endosomes.Cooperative interaction of Ig(alpha) and Ig(beta) of the BCR regulates the kinetics and specificity of antigen targeting.Phosphoinositide 3-Kinase Activation by Igβ Controls de Novo Formation of an Antigen-processing Compartment
P2860
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P2860
Syk tyrosine kinase and B cell antigen receptor (BCR) immunoglobulin-alpha subunit determine BCR-mediated major histocompatibility complex class II-restricted antigen presentation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Syk tyrosine kinase and B cell ...... stricted antigen presentation.
@en
Syk tyrosine kinase and B cell antigen receptor
@nl
type
label
Syk tyrosine kinase and B cell ...... stricted antigen presentation.
@en
Syk tyrosine kinase and B cell antigen receptor
@nl
prefLabel
Syk tyrosine kinase and B cell ...... stricted antigen presentation.
@en
Syk tyrosine kinase and B cell antigen receptor
@nl
P2093
P2860
P50
P356
P1476
Syk tyrosine kinase and B cell ...... estricted antigen presentation
@en
P2093
P2860
P304
P356
10.1084/JEM.188.5.819
P407
P577
1998-09-01T00:00:00Z