IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis.
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Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytesThe Novartis-ILAR Rheumatology Prize 2001 Osteoarthritis: from molecule to manApplications of Chondrocyte-Based Cartilage Engineering: An OverviewModeling the Insulin-Like Growth Factor System in Articular CartilageOxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways.Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage.Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disordersIntraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate.Osteoarthritis gene therapy.Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid.The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development.Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor-binding protein 3 (IGFBP-3) in human chondrocytesInsulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort.Persisting high levels of synovial fluid markers after cartilage repair: a pilot studyAssociation of hand or knee osteoarthritis with diabetes mellitus in a population of Hispanics from Puerto RicoRegulatory functions of insulin-like growth factor binding proteins in osteoarthritis.Tissue-engineering strategies to repair joint tissue in osteoarthritis: nonviral gene-transfer approaches.Identification of STAT-1 as a molecular target of IGFBP-3 in the process of chondrogenesis.Benefits of recombinant adeno-associated virus (rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression for the long-term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis.Transforming growth factor-beta1 modulates insulin-like growth factor binding protein-4 expression and proteolysis in cultured periosteal explants.Heparan sulfate regulates ADAM12 through a molecular switch mechanism.Comparison of Efficacy of Endogenous and Exogenous IGF-I in Stimulating Matrix Production in Neonatal and Mature Chondrocytes.IGFBP-5 Metabolism Is Disrupted in the Rat Medial Meniscal Tear Model of Osteoarthritis.Cartilage constructs engineered from chondrocytes overexpressing IGF-I improve the repair of osteochondral defects in a rabbit model.Damage control mechanisms in articular cartilage: the role of the insulin-like growth factor I axis.Synovium-derived stem cell-based chondrogenesis.Effect of copper on the expression of IGF-1 from chondrocytes in newborn piglets in vitro.Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis.Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes.Hsa_circ_0045714 regulates chondrocyte proliferation, apoptosis and extracellular matrix synthesis by promoting the expression of miR-193b target gene IGF1R.Effects of Artesunate on the Expressions of Insulin-Like Growth Factor-1, Osteopontin and C-Telopeptides of Type II Collagen in a Rat Model of Osteoarthritis.The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis.IGF-I induces adipose derived mesenchymal cell chondrogenic differentiation in vitro and enhances chondrogenesis in vivo.Hyaluronic Acid Influence on Normal and Osteoarthritic Tissue-Engineered Cartilage.
P2860
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P2860
IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis.
@en
type
label
IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis.
@en
prefLabel
IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis.
@en
P2093
P356
P1476
IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis.
@en
P2093
Di Battista JA
Lajeunesse D
Martel-Pelletier J
Pelletier JP
P2888
P304
P356
10.1007/S000110050288
P577
1998-03-01T00:00:00Z