The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.
about
Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteinsAPS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytesCrk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions.The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl.Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transductionThe envelope glycoprotein of friend spleen focus-forming virus covalently interacts with and constitutively activates a truncated form of the receptor tyrosine kinase Stk.Antagonizing c-Cbl enhances EGFR-dependent corneal epithelial homeostasisHeterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype.Cbl: many adaptations to regulate protein tyrosine kinases.Beyond the RING: CBL proteins as multivalent adapters.Gab1 mediates hepatocyte growth factor-stimulated mitogenicity and morphogenesis in multipotent myeloid cells.Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms.What's in a loop?Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation.C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport.Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway.Physiological Signaling and Structure of the HGF Receptor MET.
P2860
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P2860
The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
The proto-oncogene c-Cbl is a ...... e for the adaptor protein Crk.
@en
type
label
The proto-oncogene c-Cbl is a ...... e for the adaptor protein Crk.
@en
prefLabel
The proto-oncogene c-Cbl is a ...... e for the adaptor protein Crk.
@en
P2093
P2860
P356
P1433
P1476
The proto-oncogene c-Cbl is a ...... e for the adaptor protein Crk.
@en
P2093
M Garcia-Guzman
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203750
P407
P577
2000-08-01T00:00:00Z
P5875
P6179
1004860569