Role of nephrin in cell junction formation in human nephrogenesis.
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Podocin localizes in the kidney to the slit diaphragm areaCo-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formationNephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrinInsight into podocyte differentiation from the study of human genetic disease: nail-patella syndrome and transcriptional regulation in podocytesExpression of cadherin-8 in renal cell carcinoma and fetal kidneyUse of dual section mRNA in situ hybridisation/immunohistochemistry to clarify gene expression patterns during the early stages of nephron development in the embryo and in the mature nephron of the adult mouse kidneyExpression of TM4SF10, a Claudin/EMP/PMP22 family cell junction protein, during mouse kidney development and podocyte differentiationCell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complexTM4SF10 and ADAP interaction in podocytes: role in Fyn activity and nephrin phosphorylationSns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes.Advanced electron microscopic techniques provide a deeper insight into the peculiar features of podocytes.Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography.Genetic kidney diseases disclose the pathogenesis of proteinuria.Characterization of the interactions of the nephrin intracellular domain.Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytesMycophenolate mofetil and valsartan inhibit podocyte apoptosis in streptozotocin-induced diabetic rats.Nephrin promotes cell-cell adhesion through homophilic interactionsNew insights into the molecular biology of the glomerular filtration barrier and associated disease.Analysis of the cell adhesion molecule sticks-and-stones reveals multiple redundant functional domains, protein-interaction motifs and phosphorylated tyrosines that direct myoblast fusion in Drosophila melanogaster.Developmental localization of nephrin in zebrafish and medaka pronephric glomerulus.Nephrin binds to the COOH terminus of a large-conductance Ca2+-activated K+ channel isoform and regulates its expression on the cell surface.Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental TransplantationNephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros.The podocyte slit diaphragm--from a thin grey line to a complex signalling hub.Variable phenotype of Pierson syndrome.Overexpression of Myo1e in mouse podocytes enhances cellular endocytosis, migration, and adhesion.CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes.Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes.A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes.Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro.Knockdown of Tmem234 in zebrafish results in proteinuria.Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization.Localization of intercellular adherens junction protein p120 catenin during podocyte differentiation.beta-Catenin mediates adriamycin-induced albuminuria and podocyte injury in adult mouse kidneys.Rapamycin has dual opposing effects on proteinuric experimental nephropathies: is it a matter of podocyte damage?Tissue expression of nephrin in human and pig.P-Cadherin is decreased in diabetic glomeruli and in glucose-stimulated podocytes in vivo and in vitro studies.Administration of pigment epithelium-derived factor (PEDF) reduces proteinuria by suppressing decreased nephrin and increased VEGF expression in the glomeruli of adriamycin-injected rats.MAGI-1 is a component of the glomerular slit diaphragm that is tightly associated with nephrin.Recurrence of proteinuria following renal transplantation in congenital nephrotic syndrome of the Finnish type.
P2860
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P2860
Role of nephrin in cell junction formation in human nephrogenesis.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Role of nephrin in cell junction formation in human nephrogenesis.
@en
type
label
Role of nephrin in cell junction formation in human nephrogenesis.
@en
prefLabel
Role of nephrin in cell junction formation in human nephrogenesis.
@en
P2093
P2860
P1476
Role of nephrin in cell junction formation in human nephrogenesis.
@en
P2093
J Patrakka
J Wartiovaara
K Tryggvason
M Heikinheimo
P2860
P304
P356
10.1016/S0002-9440(10)64829-8
P407
P577
2000-12-01T00:00:00Z