Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney
about
Podocin localizes in the kidney to the slit diaphragm areaPodocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrinCo-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formationNephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrinCD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhereThe carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1Involvement of lipid rafts in nephrin phosphorylation and organization of the glomerular slit diaphragmTrans-interaction of nephrin and Neph1/Neph3 induces cell adhesion that associates with decreased tyrosine phosphorylation of nephrinNephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signalingCD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain.Identification of N-linked glycosylation sites in human nephrin using mass spectrometry.Identification of proteins that interact with podocin using the yeast 2-hybrid system.Regulation of Neph3 gene in podocytes--key roles of transcription factors NF-kappaB and Sp1.Inducible nephrin transgene expression in podocytes rescues nephrin-deficient mice from perinatal deathNephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release.Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography.Structural determinants of glomerular permeability.Focusing on the glomerular slit diaphragm: podocin enters the pictureDensin and filtrin in the pancreas and in the kidney, targets for humoral autoimmunity in patients with type 1 diabetes.mAb 5-1-6 nephropathy and nephrin.Regulation of adhesive interaction between podocytes and glomerular basement membrane.Densin and beta-catenin form a complex and co-localize in cultured podocyte cell junctions.Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation.The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes.Relevance of VEGF and nephrin expression in glomerular diseases.Nephrin promotes cell-cell adhesion through homophilic interactionsNew insights into the molecular biology of the glomerular filtration barrier and associated disease.Role of podocyte slit diaphragm as a filtration barrier.Clinical impact of research on the podocyte slit diaphragm.Molecular basis of the glomerular filtration: nephrin and the emerging protein complex at the podocyte slit diaphragm.Minimal change nephropathy and focal segmental glomerulosclerosis.The role of podocytes in proteinuria.Nephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros.Therapeutic target for nephrotic syndrome: Identification of novel slit diaphragm associated molecules.Role of Protein Kinase G and Reactive Oxygen Species in the Regulation of Podocyte Function in Health and Disease.Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing.Role of nephrin in cell junction formation in human nephrogenesis.Case Report: A Toddler With Anasarca Caused by Congenital Nephrotic Syndrome.Diacylglycerol Kinase alpha is Involved in the Vitamin E-Induced Amelioration of Diabetic Nephropathy in Mice.Development of kidney glomerular endothelial cells and their role in basement membrane assembly.
P2860
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P2860
Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@ast
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@en
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@nl
type
label
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@ast
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@en
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@nl
prefLabel
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@ast
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@en
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@nl
P2093
P2860
P1476
Nephrin localizes at the podoc ...... ly spliced in the human kidney
@en
P2093
A Miettinen
D Kerjaschki
H Holthöfer
P2860
P304
P356
10.1016/S0002-9440(10)65483-1
P407
P577
1999-11-01T00:00:00Z