Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross - Wikidata - awgldk - TriplyDB

Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross

Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross

http://www.wikidata.org/entity/Q41785504

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A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum PfCRT and its role in antimalarial drug resistance A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya A process similar to autophagy is associated with cytocidal chloroquine resistance in Plasmodium falciparum Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers Chlorpheniramine Analogues Reverse Chloroquine Resistance in Plasmodium falciparum by Inhibiting PfCRT.Analysis of malaria parasite phenotypes using experimental genetic crosses of Plasmodium falciparum.The landscape of inherited and de novo copy number variants in a Plasmodium falciparum genetic cross.Malaria drug resistance is associated with defective DNA mismatch repair.Plasmodium falciparum resistance to cytocidal versus cytostatic effects of chloroquine.PfCRT-mediated drug transport in malarial parasites.Analysis of chloroquine resistance transporter (CRT) isoforms and orthologues in S. cerevisiae yeast Plasmodium falciparum chloroquine resistance transporter is a H+-coupled polyspecific nutrient and drug exporter.Contrasting ex vivo efficacies of "reversed chloroquine" compounds in chloroquine-resistant Plasmodium falciparum and P. vivax isolates.Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter.Degrees of chloroquine resistance in Plasmodium - is the redox system involved?Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum.Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids.Molecular epidemiology of drug resistance markers of Plasmodium falciparum in Yunnan Province, China.Quantification of multiple infections of Plasmodium falciparum in vitro Plasmodium falciparum and Plasmodium vivax Demonstrate Contrasting Chloroquine Resistance Reversal Phenotypes.Optimized protocols for improving the likelihood of cloning recombinant progeny from Plasmodium yoelii genetic crosses.Combinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum.Functional Comparison of 45 Naturally Occurring Isoforms of the Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT).Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.To kill or not to kill, that is the question: cytocidal antimalarial drug resistance.Function of resistance conferring Plasmodium falciparum chloroquine resistance transporter isoforms.Genetic linkage analyses redefine the roles of PfCRT and PfMDR1 in drug accumulation and susceptibility in Plasmodium falciparum.Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue.Genetic predisposition favors the acquisition of stable artemisinin resistance in malaria parasites.SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum malaria parasites Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine

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Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross

http://www.wikidata.org/entity/Q41785504

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Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross

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Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross

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Molecular Microbiology

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Chloroquine susceptibility and reversibility in a Plasmodium falciparum genetic cross

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Bingbing Deng

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Drew Thacker

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Jigar J Patel

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John C Tan

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Joseph M Gonzales

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Lisa Checkley

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Michael T Ferdig

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Paul D Roepe

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Perri Pleeter

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Roland A Cooper

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P2860

Recombination hotspots and population structure in Plasmodium falciparum

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin.

Evidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial Agents

A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum

Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum

Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification

Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

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10.1111/J.1365-2958.2010.07366.X

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Plasmodium falciparum

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