Qualification of a free ligand assay in the presence of anti-ligand antibody Fab fragments.
about
Characterization of a quantitative method to measure free proprotein convertase subtilisin/kexin type 9 in human serum.Utility of free and total target measurements as target engagement and efficacy biomarkers in biotherapeutic development--opportunities and challenges.Impact of Shed/Soluble targets on the PK/PD of approved therapeutic monoclonal antibodies.Mechanistic pharmacokinetic/target engagement/pharmacodynamic (PK/TE/PD) modeling in deciphering interplay between a monoclonal antibody and its soluble target in cynomolgus monkeys.Free analyte QC concept: a novel approach to prove correct quantification of free therapeutic protein drug/biomarker concentrations.Immunoaffinity LC-MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker.
P2860
Qualification of a free ligand assay in the presence of anti-ligand antibody Fab fragments.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Qualification of a free ligand ...... ligand antibody Fab fragments.
@en
type
label
Qualification of a free ligand ...... ligand antibody Fab fragments.
@en
prefLabel
Qualification of a free ligand ...... ligand antibody Fab fragments.
@en
P2093
P2860
P356
P1476
Qualification of a free ligand ...... ligand antibody Fab fragments.
@en
P2093
Robin M Brown
Ryan J Hansen
Victor J Wroblewski
P2860
P304
P356
10.4161/MABS.23508
P577
2013-02-08T00:00:00Z