Inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by a lipophilic inactivator of cysteine endopeptidases.
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Cathepsin B in osteoarthritis: cytochemical and histochemical analysis of human femoral head cartilage.In vivo model of cartilage degradation--effects of a matrix metalloproteinase inhibitor.Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins.ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfateNeuropeptides contribute to peripheral nociceptive sensitization by regulating interleukin-1β production in keratinocytesCellular proteolysis. An overview.Inhibition of bone resorption by selective inactivators of cysteine proteinases.Falcipain-2 inhibitors.Stromelysin 1, neutrophil collagenase, and collagenase 3 do not play major roles in a model of chondrocyte mediated cartilage breakdown.Amelioration of experimental arthritis by a calpain-inhibitory compound: regulation of cytokine production by E-64-d in vivo and in vitro."Aggrecanase" activity is implicated in tumour necrosis factor alpha mediated cartilage aggrecan breakdown but is not detected by an in vitro assay.Proteolytic mechanisms of cartilage breakdown: a target for arthritis therapy?Inhibitors of collagenase but not of gelatinase reduce cartilage explant proteoglycan breakdown despite only low levels of matrix metalloproteinase activity.Inhibition of interleukin 1 beta induced rat and human cartilage degradation in vitro by the metalloproteinase inhibitor U27391.Lysosomal cysteine endopeptidases mediate interleukin 1-stimulated cartilage proteoglycan degradationEvidence that the inhibition of cartilage proteoglycan breakdown by mannosamine is not mediated via inhibition of glycosylphosphatidylinositol anchor formation.The effect of suramin on the resorption of bovine nasal cartilage.Differential Expression of Aggrecanase and Matrix Metalloproteinase Activity in Chondrocytes Isolated from Bovine and Porcine Articular Cartilage
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P2860
Inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by a lipophilic inactivator of cysteine endopeptidases.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Inhibition of interleukin 1-st ...... or of cysteine endopeptidases.
@en
type
label
Inhibition of interleukin 1-st ...... or of cysteine endopeptidases.
@en
prefLabel
Inhibition of interleukin 1-st ...... or of cysteine endopeptidases.
@en
P2093
P2860
P356
P1433
P1476
Inhibition of interleukin 1-st ...... or of cysteine endopeptidases.
@en
P2093
A J Barrett
D J Buttle
J Saklatvala
P2860
P304
P356
10.1042/BJ2810175
P407
P478
281 ( Pt 1)
P577
1992-01-01T00:00:00Z