Inhibition of bone resorption by selective inactivators of cysteine proteinases.
about
Tartrate-resistant purple acid phosphatase is synthesized as a latent proenzyme and activated by cysteine proteinasesProteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identificationBone microenvironment modulates expression and activity of cathepsin B in prostate cancer.Intracellular membrane trafficking in bone resorbing osteoclasts.Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient miceCathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts.Autocatalytic activation of human cathepsin K.A Track Record on SHOX: From Basic Research to Complex Models and TherapyVEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation.Cathepsin L in metastatic bone disease: therapeutic implications.DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets.Regulated proteolysis of nonmuscle myosin IIA stimulates osteoclast fusion.Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass.Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype.Control mechanisms in bone resorption: 240 years after John Hunter.Cytokines modulate routes of collagen breakdown. Review with special emphasis on mechanisms of collagen degradation in the periodontium and the burst hypothesis of periodontal disease progression.Mechanisms of connective tissue matrix destruction in periodontitis.Expression of human cathepsin K in Pichia pastoris and preliminary crystallographic studies of an inhibitor complex.An overview of bone cells and their regulating factors of differentiation.Insulin-like growth factor II receptor-mediated intracellular retention of cathepsin B is essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus.Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles.Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase.Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix.Quantification of the expression levels of lysosomal cysteine proteinases in purified human osteoclastic cells by competitive RT-PCR.Regulation of cell growth by redox-mediated extracellular proteolysis of platelet-derived growth factor receptor beta.
P2860
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P2860
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
@ast
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
@en
type
label
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
@ast
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
@en
prefLabel
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
@ast
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
@en
P2093
P2860
P356
P1476
Inhibition of bone resorption by selective inactivators of cysteine proteinases.
@en
P2093
Reynolds JJ
P2860
P304
P356
10.1002/JCB.240560116
P577
1994-09-01T00:00:00Z