The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization.
about
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylationCarboxypeptidase E: a negative regulator of the canonical Wnt signaling pathwayMutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathwaysMolecular basis of Wnt activation via the DIX domain protein Ccd1Wnt/beta-catenin signaling and small molecule inhibitorsWnt/beta-catenin signaling: components, mechanisms, and diseasesDishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-cateninDifferential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3Development of anticancer agents targeting the Wnt/β-catenin signalingKeeping Wnt signalosome in check by vesicular trafficThe role of Ryk and Ror receptor tyrosine kinases in Wnt signal transductionMitotic and mitogenic Wnt signallingEvolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2Peeling away the layers of ubiquitin signaling complexities with synthetic ubiquitin-protein conjugates.Tankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt SignalingAberrant regulation of Wnt signaling in hepatocellular carcinomaIdentification of transmembrane protein 88 (TMEM88) as a dishevelled-binding proteinTiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neuronsAxin cancer mutants form nanoaggregates to rewire the Wnt signaling networkThe β-catenin destruction complexTherapeutic use of PDZ protein-protein interaction antagonismBeta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumoursNaked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenindifferent Roles for the axin interactions with the SAMP versus the second twenty amino acid repeat of adenomatous polyposis coliDishevelled-2 docks and activates Src in a Wnt-dependent mannerA new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein.Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerizationIn vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryosThe structural and functional determinants of the Axin and Dishevelled DIX domainsMutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signalingModulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1.Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2.Biophysical and molecular-dynamics studies of phosphatidic acid binding by the Dvl-2 DEP domain.GSK3: a multifaceted kinase in Wnt signaling.Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA.Increased expression of colonic Wnt9A through Sp1-mediated transcriptional effects involving arylsulfatase B, chondroitin 4-sulfate, and galectin-3Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling.Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.
P2860
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P2860
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization.
@en
type
label
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization.
@en
prefLabel
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization.
@en
P2093
P356
P1476
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization.
@en
P2093
Akira Kikuchi
Marc Fiedler
Mariann Bienz
Naoki Shibata
P Jonathan G Butler
Thomas Schwarz-Romond
Yoshiki Higuchi
P2888
P304
P356
10.1038/NSMB1247
P577
2007-05-27T00:00:00Z
P5875
P6179
1010647354