Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
about
KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancerRole of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagyEGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistanceA reactive oxygen species-mediated, self-perpetuating loop persistently activates platelet-derived growth factor receptor αOncosuppressive functions of decorinAdvances in Autophagy Regulatory MechanismsVimentin in Bacterial InfectionsAutophagy and Apoptotic Crosstalk: Mechanism of Therapeutic Resistance in HER2-Positive Breast CancerAutophagy signal transduction by ATG proteins: from hierarchies to networksRedox control of protein degradationThe cytoskeleton in cell-autonomous immunity: structural determinants of host defenceMitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer TherapySelf-consumption: the interplay of autophagy and apoptosisFOXO transcription factors: key regulators of cellular quality controlThe interplay of reovirus with autophagyAutophagy in malignant transformation and cancer progressionPost-translational modifications of intermediate filament proteins: mechanisms and functionsStructure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart DiseaseRoles of autophagy induced by natural compounds in prostate cancerDifferential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagyModulation of inflammation by autophagy: Consequences for human diseaseATG16L1: A multifunctional susceptibility factor in Crohn diseaseInsights into the key roles of proteoglycans in breast cancer biology and translational medicineRegulation of autophagy by Beclin 1 in the heartAutophagy-Induced Apoptosis in Lung Cancer Cells by a Novel Digitoxin AnalogOxidative stress and autophagy: the clash between damage and metabolic needsNADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's diseaseAssociation of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humansIdentification of a Transcription Factor That Regulates Host Cell Exit and Virulence of Mycobacterium tuberculosisKnockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cellsRegulation of Beclin 1 Protein Phosphorylation and Autophagy by Protein Phosphatase 2A (PP2A) and Death-associated Protein Kinase 3 (DAPK3).Post-translationally-modified structures in the autophagy machinery: an integrative perspective.mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseasesA second wave of Salmonella T3SS1 activity prolongs the lifespan of infected epithelial cells.Vimentin is a potential prognostic factor for tongue squamous cell carcinoma among five epithelial-mesenchymal transition-related proteins.Fhit, a tumor suppressor protein, induces autophagy via 14-3-3τ in non-small cell lung cancer cells.Foxo3a-dependent Bim transcription protects mice from a high fat diet via inhibition of activation of the NLRP3 inflammasome by facilitating autophagy flux in Kupffer cells.ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 lossAvian reovirus p17 and σA act cooperatively to downregulate Akt by suppressing mTORC2 and CDK2/cyclin A2 and upregulating proteasome PSMB6.
P2860
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P2860
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
@en
type
label
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
@en
prefLabel
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
@en
P2093
P2860
P356
P1433
P1476
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
@en
P2093
Beth Levine
Guanghua Xiao
Julia Reichelt
Michael White
Richard C Wang
Yongjie Wei
Zhongju Zou
P2860
P304
P356
10.1126/SCIENCE.1225967
P407
P577
2012-10-25T00:00:00Z