Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death.
about
Repression of Puma by scratch2 is required for neuronal survival during embryonic developmentMouse models for radiation-induced cancersHow cell death shapes cancerPredisposition to cancer caused by genetic and functional defects of mammalian Atad5Cyclooxygenase-2: A Role in Cancer Stem Cell Survival and Repopulation of Cancer Cells during TherapyIL-7Rα deficiency in p53null mice exacerbates thymocyte telomere erosion and lymphomagenesisp53-Dependent transcriptional responses to interleukin-3 signalingGenetic variants of NOXA and MCL1 modify the risk of HPV16-associated squamous cell carcinoma of the head and neck.Expression of Bim, Noxa, and Puma in non-small cell lung cancerReactive oxygen species in normal and tumor stem cells.Uncoupling p53 functions in radiation-induced intestinal damage via PUMA and p21.Recent advances in p53 research and cancer treatmentp53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome.Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.The p53-PUMA axis suppresses iPSC generationAntagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress.Pharmacological blockade of Bcl-2, Bcl-x(L) and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice.BH3-only proteins in apoptosis at a glanceThe BCL-2 protein family, BH3-mimetics and cancer therapy.Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphomaInhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndromeDNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and NoxaRepression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance.The loss of the BH3-only Bcl-2 family member Bid delays T-cell leukemogenesis in Atm-/- miceParp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in micePUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia.The enigmatic roles of caspases in tumor developmentInterrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasisStrange attractors: DAMPs and autophagy link tumor cell death and immunity.Hematopoietic stem cell injury induced by ionizing radiation.BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis.Apoptosis promotes early tumorigenesis.Apoptosis and oncogenesis: give and take in the BCL-2 family.Deciphering the rules of programmed cell death to improve therapy of cancer and other diseasesPUMA, a critical mediator of cell death--one decade on from its discovery.The role of the apoptotic machinery in tumor suppression.Regulation of hematopoietic stem cell integrity through p53 and its related factors.Bcl-2 proteins in development, health, and disease of the hematopoietic system.PUMA-dependent apoptosis in NSCLC cancer cells by a dimeric β-carboline.
P2860
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P2860
Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Apoptosis-promoted tumorigenes ...... s Puma-driven leukocyte death.
@en
type
label
Apoptosis-promoted tumorigenes ...... s Puma-driven leukocyte death.
@en
prefLabel
Apoptosis-promoted tumorigenes ...... s Puma-driven leukocyte death.
@en
P2093
P2860
P50
P356
P1433
P1476
Apoptosis-promoted tumorigenes ...... es Puma-driven leukocyte death
@en
P2093
Alex R D Delbridge
Cassandra J Vandenberg
Clare L Scott
P2860
P304
P356
10.1101/GAD.1940110
P577
2010-08-01T00:00:00Z