Inhibition of MTOR disrupts autophagic flux in podocytes. - Wikidata - awgldk - TriplyDB

Inhibition of MTOR disrupts autophagic flux in podocytes.

Inhibition of MTOR disrupts autophagic flux in podocytes.

http://www.wikidata.org/entity/Q41812610

about

Podocytes 5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complications Autophagy: A Novel Therapeutic Target for Diabetic Nephropathy Autophagy and the (Pro)renin Receptor The role of autophagy in the pathogenesis of diabetic nephropathy The function of endocytosis in podocytes Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury Autophagy in kidney health and disease.(Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose.Podocytes degrade endocytosed albumin primarily in lysosomes Podocytes, signaling pathways, and vascular factors in diabetic kidney disease Dysregulated autophagy contributes to podocyte damage in Fabry's disease.Phosphorylation of ribosomal protein S6 mediates compensatory renal hypertrophy Insight into response to mTOR inhibition when PKD1 and TSC2 are mutated Understanding the mechanisms of proteinuria: therapeutic implications Autophagy in kidney transplants of sirolimus treated recipients mVps34 deletion in podocytes causes glomerulosclerosis by disrupting intracellular vesicle trafficking.MOF maintains transcriptional programs regulating cellular stress response.A first in man, dose-finding study of the mTORC1/mTORC2 inhibitor OSI-027 in patients with advanced solid malignancies.Autophagy and metabolic changes in obesity-related chronic kidney disease.Mammalian tribbles homologs at the crossroads of endoplasmic reticulum stress and Mammalian target of rapamycin pathways.Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes.Role of FOXO1 in aldosterone-induced autophagy: a compensatory protective mechanism related to podocyte injury.Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury Activation of mTORC1 in collecting ducts causes hyperkalemia.Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?Influence of autophagy on the efficacy of radiotherapy.Notoginsenoside R1 attenuates glucose-induced podocyte injury via the inhibition of apoptosis and the activation of autophagy through the PI3K/Akt/mTOR signaling pathway.Insulin signalling to the kidney in health and disease.Looking at the (w)hole: magnet resonance imaging in polycystic kidney disease.Mitochondrial dysfunction in the pathophysiology of renal diseases.mTOR signaling in autophagy regulation in the kidney.mTOR controls kidney epithelia in health and disease.Novel targets of antifibrotic and anti-inflammatory treatment in CKD.Mechanisms and biological functions of autophagy in diseased and ageing kidneys.Cell biology of diabetic nephropathy: Roles of endothelial cells, tubulointerstitial cells and podocytes Everolimus for renal angiomyolipoma in patients with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis: extension of a randomized controlled trial.Renal Toxicities of Targeted Therapies.Association of podocyte autophagosome numbers with idiopathic membranous nephropathy and secondary membranous nephropathy.mTOR inhibitors in pancreas transplant: adverse effects and drug-drug interactions.

P2860

Q26766118-C000CF9A-8D29-4D5F-BA64-50706A56D3A8 Q26767331-CC35739B-EE1F-49DC-860F-8150F7274E18 Q26771919-5483B1A3-1B7F-4EA6-BB2B-D129BFABBDD4 Q26849212-6633B57F-C3EC-4397-AFEB-B4271BBCD90A Q26851073-E185D3CF-6E38-4FD7-B25F-8FE4994E3BD6 Q27006914-33C9B173-1675-43AE-BB13-E945B6368139 Q27330163-D66E3A81-5442-4A65-A5B6-26C347A58EBA Q27687496-B3605159-D3E3-485C-B9CC-64A987BADEF3 Q30279173-A2FA5965-B55B-45B7-8714-5DB6DEF4975E Q33748757-FE02BA79-FE4C-4309-A83B-06B0996BE1E8 Q33821237-DB23F1B0-C7E6-49B1-B6F4-8219F396B232 Q34730562-38F15DCD-7DB3-4064-B419-D034170DE0CA Q35132442-B130EF1A-1BC1-44B3-8621-9BD48B35F656 Q35664471-92E55E50-3B8A-42F3-82E0-3035F334F12B Q36100123-C80D44DD-018D-4E7F-95CE-8B03F567FBA8 Q36368447-64974F69-4DDF-4F40-A6B6-5A618742E198 Q36574743-CCB7F497-E197-436C-BC73-518BD5DE1E73 Q36970331-C4912EB6-8C2D-46FC-8D7D-B2F8D68C2FD1 Q37174723-3AF7D8F1-0027-4308-883A-80A755E4EA07 Q37270835-B6FC4B57-048B-45DF-9685-3B2DEC2E00A4 Q37481737-5A48E0E3-B12D-45FE-8F0C-747CB3087C96 Q37557563-84D0F07C-4F81-49A9-8E5D-5278A1FEF503 Q37564416-EBECD308-D723-4C95-8143-9D40947E3ED1 Q37597721-CA235876-3984-4F4D-AA5C-C93470AC6107 Q37604717-75442316-9E08-4EAB-A933-5552BC53B470 Q37686261-B0DC81FF-C052-44DE-AEB1-D37E1AA45AE6 Q37713509-FD491EEC-BDC4-4656-8623-B8E1B3C7C9FF Q37713980-E81484F6-FE58-4B60-97FC-908D058863B4 Q38063325-1AF7DD52-83EA-4E07-8D39-465F63288E92 Q38067358-6874231D-87CC-48A9-855A-BE5071AB8C69 Q38168664-837D0F6A-80D1-4006-A460-E2052D6E5C9D Q38184060-55C02CC8-7678-4DA6-AEFE-C394B844B34C Q38185017-D97CFD08-3DB9-479F-8DA1-A5D7EDFE513D Q38198872-84ABFB23-C550-4AEC-A882-271EEB47A9D1 Q38266793-E663168C-19CB-4BFE-AC80-DFD9188D7A76 Q38332511-3E5F330E-E029-41E0-BFAC-F607C89713D3 Q38408393-6577EA79-FF6E-4483-9054-7E10A400E2AC Q38448007-16D87981-90FC-4C8C-8CF8-FAFD23EDFA83 Q38912864-4691B1F3-05A1-4F45-9093-29484C7FC813 Q38962103-B1DEBADB-C3F6-4B23-AAD1-A0854B7B9A84

P2860

Inhibition of MTOR disrupts autophagic flux in podocytes.

http://www.wikidata.org/entity/Q41812610

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Inhibition of MTOR disrupts autophagic flux in podocytes.

@en

type

label

Inhibition of MTOR disrupts autophagic flux in podocytes.

@en

prefLabel

Inhibition of MTOR disrupts autophagic flux in podocytes.

@en

P1433

Q41812610-B63C8A44-0B69-4005-84E8-6265C833D8FE

P1476

Q41812610-E6C602D7-F2F9-4E0B-9FAC-6532A59F1EE2

P2093

Q41812610-1D74C8B9-1A94-4D4D-987E-CD2167AA96D7

Q41812610-2AB39CB7-ABB9-4BEB-8FA2-68538F3D46EE

Q41812610-2B918666-9333-4FEF-A4C4-4F957C7552D0

Q41812610-5BE93260-ACF3-49D9-9B61-63B7EFC01CDF

Q41812610-6B55005D-4512-4184-86DA-4DD34307AD98

Q41812610-A48A36B4-CE64-495C-B126-1335C28FE370

Q41812610-D27E61F4-67A6-4734-9B2C-E1E80BED908B

Q41812610-DB57D963-4A37-4F67-8D97-4D4B9A098A17

P2860

Q41812610-09332F23-96B4-4FB6-AD56-74D101823F6C

Q41812610-1111607E-BB70-4873-ADE5-5A9E3825A6F7

Q41812610-173ED390-7E28-46FE-A178-818CC623FBC6

Q41812610-1A917E5F-03F3-4018-B341-F699851A41B9

Q41812610-1B3776C9-7EC1-437A-B1C7-940773F913FE

Q41812610-2064C088-0D3C-4B58-A021-76E4399F2E25

Q41812610-23D92EE9-6A1B-41A7-8A54-3AB712EE9C51

Q41812610-248BC0DC-6255-444A-BC27-E5FC5FF2ADF2

Q41812610-316552E4-3E49-4714-B468-594064E9D5E9

Q41812610-31DC223B-C08D-436C-903C-F37A01BC043C

P304

Q41812610-AA5F9862-5D25-46B7-AED6-A42C8A12ACF1

P31

Q41812610-87F43DBE-ECFA-46A8-833F-135BE31DB082

P356

Q41812610-EE37FA28-B79D-4ABD-83FA-5D4A99D16B11

P433

Q41812610-6811D7EE-4C88-4F5F-B5D0-CD78FE4A6A03

P478

Q41812610-29DE4A9A-1DE4-42E4-A8E4-EC807D95C70E

P577

Q41812610-11463BAC-CD61-4305-8D7B-CCCF190D714A

P698

Q41812610-FCDDF461-83EF-4138-9CB5-2F6B79F6B8E3

P932

Q41812610-0EA9E8A9-BFD4-48FA-88E6-61C08BD20587

P356

P1433

Journal of the American Society of Nephrology

P1476

Inhibition of MTOR disrupts autophagic flux in podocytes.

@en

P2093

Aarti Paltoo

http://www.w3.org/2001/XMLSchema#string

Andrea Jurisicova

http://www.w3.org/2001/XMLSchema#string

Chengjin Li

http://www.w3.org/2001/XMLSchema#string

Davide P Cinà

http://www.w3.org/2001/XMLSchema#string

Javier De Arteaga

http://www.w3.org/2001/XMLSchema#string

Susan E Quaggin

http://www.w3.org/2001/XMLSchema#string

Tuncer Onay

http://www.w3.org/2001/XMLSchema#string

Yoshiro Maezawa

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

VEGF inhibition and renal thrombotic microangiopathy

mTOR: from growth signal integration to cancer, diabetes and ageing

Autophagy fights disease through cellular self-digestion

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

A highly efficient recombineering-based method for generating conditional knockout mutations

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

P304

412-420

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1681/ASN.2011070690

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

23

http://www.w3.org/2001/XMLSchema#string

P577

2011-12-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

22193387

http://www.w3.org/2001/XMLSchema#string

P932

3294311

http://www.w3.org/2001/XMLSchema#string