Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues.
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Molecular and clinical profiles of syndecan-1 in solid and hematological cancer for prognosis and precision medicineStructural characterization of human heparanase reveals insights into substrate recognition.PG545 enhances anti-cancer activity of chemotherapy in ovarian models and increases surrogate biomarkers such as VEGF in preclinical and clinical plasma samplesHeparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activationThe Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrenceHeparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases.Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease.Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase.Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545.Heparin Mimetics: Their Therapeutic Potential.Making an impact: FEBS Open Bio celebrates its 3rd anniversary.Making an impact: FEBS Open Bio celebrates its 3rd anniversary.Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors.
P2860
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P2860
Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analogues.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Mechanisms of heparanase inhib ...... nd three structural analogues.
@en
type
label
Mechanisms of heparanase inhib ...... nd three structural analogues.
@en
prefLabel
Mechanisms of heparanase inhib ...... nd three structural analogues.
@en
P2093
P2860
P1433
P1476
Mechanisms of heparanase inhib ...... nd three structural analogues.
@en
P2093
Edward Hammond
Ian Bytheway
Keith Dredge
Paul Handley
P2860
P304
P356
10.1016/J.FOB.2013.07.007
P577
2013-08-02T00:00:00Z