Early and late events induced by polyQ-expanded proteins: identification of a common pathogenic property of polYQ-expanded proteins.
about
Chaperone-like activity of high-mobility group box 1 protein and its role in reducing the formation of polyglutamine aggregatesNOX signaling in molecular cardiovascular mechanisms involved in the blood pressure homeostasisAtaxin-2 modulates the levels of Grb2 and SRC but not ras signaling.New insights on NOX enzymes in the central nervous system.Spinocerebellar Ataxia Type 2 Is Associated with the Extracellular Loss of Superoxide Dismutase but Not Catalase Activity.Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model.Ser46 phosphorylation and prolyl-isomerase Pin1-mediated isomerization of p53 are key events in p53-dependent apoptosis induced by mutant huntingtin.Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.Elevated NADPH oxidase activity contributes to oxidative stress and cell death in Huntington's disease.Neuronal Ca(2+) dyshomeostasis in Huntington disease.Nox NADPH oxidases and the endoplasmic reticulumPotential therapeutic targets in polyglutamine-mediated diseases.Role of mitochondrial raft-like microdomains in the regulation of cell apoptosis.Is membrane homeostasis the missing link between inflammation and neurodegenerative diseases?PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.Reactive Oxygen Species Derived from NOX3 and NOX5 Drive Differentiation of Human Oligodendrocytes.TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis.Long Term Aggresome Accumulation Leads to DNA Damage, p53-dependent Cell Cycle Arrest, and Steric Interference in Mitosis.Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.hMTH1 expression protects mitochondria from Huntington's disease-like impairment.In vitro and in vivo aggregation of a fragment of huntingtin protein directly causes free radical production.A Drosophila model of Huntington disease-like 2 exhibits nuclear toxicity and distinct pathogenic mechanisms from Huntington disease.RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.Adult-onset autosomal recessive ataxia associated with neuronal ceroid lipofuscinosis type 5 gene (CLN5) mutations.
P2860
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P2860
Early and late events induced by polyQ-expanded proteins: identification of a common pathogenic property of polYQ-expanded proteins.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Early and late events induced ...... ty of polYQ-expanded proteins.
@en
type
label
Early and late events induced ...... ty of polYQ-expanded proteins.
@en
prefLabel
Early and late events induced ...... ty of polYQ-expanded proteins.
@en
P2093
P2860
P356
P1476
Early and late events induced ...... ty of polYQ-expanded proteins.
@en
P2093
Alessandra Bertoni
Deborah Rotoli
Luca Ulianich
Maria Rosaria Santillo
Mario Galgani
Paola Giuliano
Vittorio Enrico Avvedimento
P2860
P304
P356
10.1074/JBC.M110.156521
P407
P577
2010-11-28T00:00:00Z