REST/NRSF-mediated intrinsic homeostasis protects neuronal networks from hyperexcitability.
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The Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases(1,2,3)The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes.Neurite outgrowth induced by NGF or L1CAM via activation of the TrkA receptor is sustained also by the exocytosis of enlargeosomes.An RNA binding protein promotes axonal integrity in peripheral neurons by destabilizing REST.Regulation of neural gene transcription by optogenetic inhibition of the RE1-silencing transcription factorREST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.Signal transduction of the physical environment in the neural differentiation of stem cells.RE-1 silencing transcription factor (REST): a regulator of neuronal development and neuronal/endocrine function.NRSF: an angel or a devil in neurogenesis and neurological diseases.Epigenetic mechanisms in neurological and neurodegenerative diseases.REST-Dependent Presynaptic Homeostasis Induced by Chronic Neuronal Hyperactivity.Brain REST/NRSF Is Not Only a Silent Repressor but Also an Active Protector.The role of REST and HDAC2 in epigenetic dysregulation of Nav1.5 and nNav1.5 expression in breast cancer.Plasma REST: a novel candidate biomarker of Alzheimer's disease is modified by psychological intervention in an at-risk populationExtracellular signal-related kinase 2/specificity protein 1/specificity protein 3/repressor element-1 silencing transcription factor pathway is involved in Aroclor 1254-induced toxicity in SH-SY5Y neuronal cells.Yin-yang actions of histone methylation regulatory complexes in the brain.Epigenetic interventions for epileptogenesis: A new frontier for curing epilepsy.Down-regulation of neuronal L1 cell adhesion molecule expression alleviates inflammatory neuronal injury.Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation.Epigenomics of Neural Cells: REST-Induced Down- and Upregulation of Gene Expression in a Two-Clone PC12 Cell Model.Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy.Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome.
P2860
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P2860
REST/NRSF-mediated intrinsic homeostasis protects neuronal networks from hyperexcitability.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
REST/NRSF-mediated intrinsic h ...... tworks from hyperexcitability.
@en
type
label
REST/NRSF-mediated intrinsic h ...... tworks from hyperexcitability.
@en
prefLabel
REST/NRSF-mediated intrinsic h ...... tworks from hyperexcitability.
@en
P2093
P2860
P50
P356
P1433
P1476
REST/NRSF-mediated intrinsic h ...... etworks from hyperexcitability
@en
P2093
Davide Boido
Enrico Ferrea
Fabio Benfenati
Gabriele Lignani
Jacopo Meldolesi
Pietro Baldelli
Rosalba D'Alessandro
P2860
P304
P356
10.1038/EMBOJ.2013.231
P407
P577
2013-10-22T00:00:00Z