Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells.
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Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular riskNitric oxide synthases in mammalsInhibition by N-acetyl-5-hydroxytryptamine of nitric oxide synthase expression in cultured cells and in the anaesthetized ratStimulation of human nitric oxide synthase by tetrahydrobiopterin and selective binding of the cofactorAging and vascular endothelial function in humansGTP cyclohydrolase 1 inhibition attenuates vasodilation and increases blood pressure in ratsInduction of GTP cyclohydrolase I by bacterial lipopolysaccharide in the ratRole of tetrahydrobiopterin in resistance to myocardial ischemia in Brown Norway and Dahl S rats.Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia.L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin.Regulation of pteridine-requiring enzymes by the cofactor tetrahydrobiopterin.Tetrahydrobiopterin, superoxide, and vascular dysfunction.Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults.Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity.The two faces of endothelial nitric oxide synthase in the pathophysiology of atherosclerosis.Correlations between Endothelial Functions and ROS Detection in Diabetic Microvascular Wall: Early and Late Ascorbic Acid Supplementation.Cyclooxygenase inhibition augments central blood pressure and aortic wave reflection in aging humansErythropoietin increases endothelial biosynthesis of tetrahydrobiopterin by activation of protein kinase B alpha/Akt1.Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats.Beneficial effects of polyphenol-rich olive oil in patients with early atherosclerosis.Peripheral circulation.Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.Inhibition of proteasome-mediated glucocorticoid receptor degradation restores nitric oxide bioavailability in myocardial endothelial cells in vitro.The arginine-nitric oxide pathway: a target for new drugs.Regulation of nitric oxide synthase and soluble guanylyl cyclase.Nitric oxide/cyclic GMP-mediated signal transduction.Comparison of neuronal and endothelial isoforms of nitric oxide synthase in stably transfected HEK 293 cells.S-nitrosation controls gating and conductance of the alpha 1 subunit of class C L-type Ca(2+) channels.Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin.Release by ultraviolet B (u.v.B) radiation of nitric oxide (NO) from human keratinocytes: a potential role for nitric oxide in erythema production.Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis.Tetrahydrobiopterin cofactor biosynthesis: GTP cyclohydrolase I mRNA expression in rat brain and superior cervical ganglia.Increases in endothelial cyclic AMP levels amplify agonist-induced formation of endothelium-derived relaxing factor (EDRF).Complex trait genetics the role of mechanistic "intermediate phenotypes" and candidate genetic loci.An important role of increase in tetrahydrobiopterin via H2O2-JAK2 signalling pathway in late phase of ischaemic preconditioning.Oxidation of tetrahydrobiopterin by peroxynitrite or oxoferryl species occurs by a radical pathway.The effect of insufficiency of tetrahydrobiopterin on endothelial function and vasoactivity.Dexamethasone suppresses iNOS yet induces GTPCH and CAT-2 mRNA expression in rat lungs.1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide.
P2860
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P2860
Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Tetrahydrobiopterin-dependent ...... ) in aortic endothelial cells.
@en
type
label
Tetrahydrobiopterin-dependent ...... ) in aortic endothelial cells.
@en
prefLabel
Tetrahydrobiopterin-dependent ...... ) in aortic endothelial cells.
@en
P2093
P2860
P356
P1433
P1476
Tetrahydrobiopterin-dependent ...... ) in aortic endothelial cells.
@en
P2093
P2860
P304
P356
10.1042/BJ2810297
P407
P478
281 ( Pt 2)
P577
1992-01-01T00:00:00Z