Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. - Wikidata - awgldk - TriplyDB

Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones.

Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones.

http://www.wikidata.org/entity/Q41836294

about

The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin Serine-arginine protein kinases: a small protein kinase family with a large cellular presence SR proteins in vertical integration of gene expression from transcription to RNA processing to translation Chaperones in hepatitis C virus infection Posttranscriptional Regulation of Splicing Factor SRSF1 and Its Role in Cancer Cell Biology Splicing Regulators and Their Roles in Cancer Biology and Therapy Phosphorylation-mediated regulation of alternative splicing in cancer Context-dependent control of alternative splicing by RNA-binding proteins Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)Applying the brakes to multisite SR protein phosphorylation: substrate-induced effects on the splicing kinase SRPK1 Paraquat modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2 An Ultraconserved Element (UCE) controls homeostatic splicing of ARGLU1 mRNA.Both decreased and increased SRPK1 levels promote cancer by interfering with PHLPP-mediated dephosphorylation of Akt.Regulation of the subcellular distribution of key cellular RNA-processing factors during permissive human cytomegalovirus infection Elevated SRPK1 lessens apoptosis in breast cancer cells through RBM4-regulated splicing events.Mitochondrial complex 1 inhibition increases 4-repeat isoform tau by SRSF2 upregulation.Human papillomavirus type 1 E1^E4 protein is a potent inhibitor of the serine-arginine (SR) protein kinase SRPK1 and inhibits phosphorylation of host SR proteins and of the viral transcription and replication regulator E2 Induction of viral, 7-methyl-guanosine cap-independent translation and oncolysis by mitogen-activated protein kinase-interacting kinase-mediated effects on the serine/arginine-rich protein kinase.Functional consequences of developmentally regulated alternative splicing.Specific inhibition of serine/arginine-rich protein kinase attenuates choroidal neovascularization.In vitro characterization of the RS motif in N-terminal head domain of goldfish germinal vesicle lamin B3 necessary for phosphorylation of the p34cdc2 target serine by SRPK1 Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1 New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor.Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage.Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2.The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2 Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance.Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma.The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus.Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization Nucleotide release sequences in the protein kinase SRPK1 accelerate substrate phosphorylation.SRPK1 Dissimilarly Impacts on the Growth, Metastasis, Chemosensitivity and Angiogenesis of Glioma in Normoxic and Hypoxic Conditions.The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells.Degrade, move, regroup: signaling control of splicing proteins.

P2860

Q24297656-5759C9FD-C27A-44E2-8D6F-C81312ACE2BE Q24310828-F8AA33BB-27B6-4BDD-A5C7-8E6C5658333B Q24316205-12F3E1B0-F830-41AF-BDDB-A0C92DF53F17 Q24323291-3D3848A4-040B-47DF-B170-762FE3F8C05D Q24654094-A4BFBBCB-8BDE-468E-8C31-4D660EABE927 Q26771251-192A65F1-1B52-4F8C-89CE-56E1DD0441E8 Q26798154-195533B4-FA6B-4756-878D-BD314B81BF8D Q26798158-ED08C004-0FAD-43CB-94B7-8DD25906132E Q27009883-50907C1F-5086-4B52-AAA2-B4E8C83485E5 Q28245737-0FBB8C66-4790-45DD-AE10-6E15C5FD35F9 Q28472268-80DD7B21-A654-4D3D-ABB1-9B8D924EA7F1 Q28547020-56EEFDAC-FE29-4244-8267-9060F0166813 Q28741625-C53E90C1-D1D7-4B74-BB2A-F24A7A7431B8 Q31115932-421AC7D8-36E6-4109-89A9-04DD3C55AC31 Q33557947-87687A53-0D35-4B8F-A3F7-D889EC81EC84 Q33605329-1DEFCA7A-6947-44EE-8633-0AE40D0BBE91 Q33923193-A01D6870-4CAB-4836-9BBE-67C66BBCFA22 Q34240895-0EE0F357-3628-4450-8EE7-C8C27F56BAD0 Q34526836-97919ADF-309D-4C88-98C1-F6BD5569022C Q34593811-B759055F-8794-4EAB-9269-5F5BE963EE26 Q34594574-7E7101C2-E21E-4F82-B742-FE622FC64429 Q34632366-99E084AB-D78B-42F3-B8F0-A7FC97D7F2B4 Q34656053-35186EA8-EE50-4320-8579-F613939DC99A Q34774699-3DBF73D7-4C26-4C59-805D-A34A019A65B0 Q35064474-3E2A968C-1A8F-499F-9ECB-94D581160E62 Q35200971-AD852374-67EC-4DAB-9A20-77300A37A4E0 Q35276828-273C0AD4-67CA-4869-9ED0-0EB0F0108C1F Q35541632-586F5605-D6BF-441D-95CC-1729AD118C33 Q35562067-22F3B4CB-3B1B-4898-8180-8B8E044A51C9 Q35691190-15F9CC42-780B-4F5A-A555-7DC89224FA73 Q35827518-97E10180-61A7-4C9F-9AB5-5429D5704388 Q36059712-D2E1CF01-131C-4517-8565-6436C9C9C4BE Q36108838-0AA044C0-7591-472A-ABE1-9EDB5A8D992F Q36161960-78DAAC82-E810-4C06-A4EE-0F871C6C2EC3 Q36271734-ED8FF6F2-4815-4E4F-810D-490BAB7AD3F0 Q37031421-4B541615-F4E4-4999-98D8-1EC98B466A2F Q37347529-8234F3EC-8DDD-476F-B0D4-0F11E4024367 Q37631845-EA09793B-AAD0-4FAC-B1D4-41D2C0423427 Q37661658-19E438D0-E315-4B83-99B8-C5B66B9002C4 Q37877384-8E1F3656-3CFE-46C4-8BB3-15C8F1B4CBC1

P2860

Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones.

http://www.wikidata.org/entity/Q41836294

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

Regulation of SR protein phosp ...... PK1 with molecular chaperones.

@en

type

label

Regulation of SR protein phosp ...... PK1 with molecular chaperones.

@en

prefLabel

Regulation of SR protein phosp ...... PK1 with molecular chaperones.

@en

P1433

Q41836294-46565F28-E1FB-491B-87ED-C0C9A503667D

P1476

Q41836294-F6957D96-550B-423E-BEE8-75E37D86611E

P2093

Q41836294-0014B299-1F08-4456-9A61-F2722A038291

Q41836294-06D1AB0C-93DB-47C4-BE77-A7069DC0DFE2

Q41836294-175E0CFE-9FBA-4156-833F-9A6943AC46E7

Q41836294-634DB786-3B8B-467D-BEC5-D4ABD4D34692

Q41836294-DFEFEC21-1D98-4EF8-B23C-45443C2C0431

P2860

Q41836294-04034336-2891-4B8C-B1E5-1A04E5250A14

Q41836294-04460719-A75E-401D-880C-5B1C081FEB01

Q41836294-0A77278E-871B-4D44-B91A-C0046CA52B28

Q41836294-0F969A51-6013-4979-B7B0-35F8A10A6B56

Q41836294-13411185-F879-4473-A35F-7701D1FE5F45

Q41836294-136838A3-2D63-458D-887E-2427571DCBC1

Q41836294-14BACFB5-8D9D-4F1C-9FC8-D6107615A5D4

Q41836294-16E57684-0995-45C0-972B-D11B05C73EAF

Q41836294-16E95E9B-B330-43A5-9CD6-FBABD9D47163

Q41836294-19BD3508-5697-42D5-8589-AB8648FCF834

P304

Q41836294-1356B2DF-9DE0-4DDE-A007-AE1132337664

P31

Q41836294-A6644BAA-E373-4D2E-9FCE-54E5912A7412

P356

Q41836294-53B3C929-6D7A-4D5A-A205-B4F318212064

P433

Q41836294-4A715B7A-001A-49E7-9549-942E925A03F9

P478

Q41836294-35F6FBA7-965A-43DF-8D1E-A2F22C465B97

P577

Q41836294-CE1C5BFA-E966-47D7-9CEB-A101CA956530

P5875

Q41836294-69E0777D-FCCA-4E10-AC9F-D46DA9CA2071

P698

Q41836294-51F0703E-5FD3-4CCB-9A5D-CB0E45C7E763

P921

Q41836294-1CAE49D8-C73B-422C-B57E-44BF182D8767

Q41836294-C311A5C5-FF63-4345-8D6A-30B677C151C9

P932

Q41836294-9CB2616E-510C-4C26-82BE-3AEC9A9BE09B

P356

P1433

Genes & Development

P1476

Regulation of SR protein phosp ...... PK1 with molecular chaperones.

@en

P2093

Gourisankar Ghosh

http://www.w3.org/2001/XMLSchema#string

Jian-Hua Ding

http://www.w3.org/2001/XMLSchema#string

Joseph A Adams

http://www.w3.org/2001/XMLSchema#string

Xiang-Dong Fu

http://www.w3.org/2001/XMLSchema#string

Xiang-Yang Zhong

http://www.w3.org/2001/XMLSchema#string

P2860

Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins

SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA

Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1

Differential effects of hyperphosphorylation on splicing factor SRp55

The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro.

P304

482-495

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.1752109

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

23

http://www.w3.org/2001/XMLSchema#string

P577

2009-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

24037734

http://www.w3.org/2001/XMLSchema#string

P698

19240134

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

molecular chaperones

P932

2648651

http://www.w3.org/2001/XMLSchema#string