Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin.
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Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathwaysNew approaches to treatment of primary immunodeficiencies: fixing mutations with chemicalsTranslational readthrough potential of natural termination codons in eucaryotes--The impact of RNA sequenceCystic fibrosis transmembrane conductance regulator dysfunction and its treatmentNonsense-mediated mRNA decay: inter-individual variability and human diseaseA combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decayAttenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppressionRobust Stimulation of W1282X-CFTR Channel Activity by a Combination of Allosteric ModulatorsEx vivo treatment with a novel synthetic aminoglycoside NB54 in primary fibroblasts from Rett syndrome patients suppresses MECP2 nonsense mutationsNovel small molecules potentiate premature termination codon readthrough by aminoglycosidesAntagonistic factors control the unproductive splicing of SC35 terminal intron.Aminoglycoside-stimulated readthrough of premature termination codons in selected genes involved in primary ciliary dyskinesia.Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues.The unfolded protein response affects readthrough of premature termination codonsHeritability in the efficiency of nonsense-mediated mRNA decay in humans.Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutationsAlternative splicing at a NAGNAG acceptor site as a novel phenotype modifier.New trends in aminoglycosides use.Cystic fibrosis transmembrane conductance regulator protein repair as a therapeutic strategy in cystic fibrosisWhen a ribosome encounters a premature termination codon.Targets for cystic fibrosis therapy: proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulatorClass 1 CF MutationsThe genetic basis of non-syndromic intellectual disability: a reviewMutations in the human laminin beta2 (LAMB2) gene and the associated phenotypic spectrum.Aminoglycoside-induced mutation suppression (stop codon readthrough) as a therapeutic strategy for Duchenne muscular dystrophyTranslational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion.Nonsense-mediated decay in genetic disease: friend or foe?A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene.Optimizing nasal potential difference analysis for CFTR modulator development: assessment of ivacaftor in CF subjects with the G551D-CFTR mutation.Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutationsSuppression of nonsense mutations as a therapeutic approach to treat genetic diseases.Activation of Type 1 CRH receptor isoforms induces serotonin release from human carcinoid BON-1N cells: an enterochromaffin cell model.A whole-genome analysis of premature termination codons.The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 subunit.Suppression of premature termination codons as a therapeutic approach.A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapiesA system for coordinated analysis of translational readthrough and nonsense-mediated mRNA decay.Premature termination codons in PRPF31 cause retinitis pigmentosa via haploinsufficiency due to nonsense-mediated mRNA decay.From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.
P2860
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P2860
Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Nonsense-mediated mRNA decay a ...... brosis patients to gentamicin.
@en
type
label
Nonsense-mediated mRNA decay a ...... brosis patients to gentamicin.
@en
prefLabel
Nonsense-mediated mRNA decay a ...... brosis patients to gentamicin.
@en
P2093
P2860
P356
P1476
Nonsense-mediated mRNA decay a ...... brosis patients to gentamicin.
@en
P2093
Andreas E Kulozik
Batsheva Kerem
Dov Virgilis
Eitan Kerem
Gabriele Neu-Yilik
Liat Linde
Malka Nissim-Rafinia
Michael Wilschanski
Stephanie Boelz
Yasmin Yaacov
P2860
P304
P356
10.1172/JCI28523
P407
P577
2007-02-08T00:00:00Z