Hyaluronan oligosaccharides inhibit tumorigenicity of osteosarcoma cell lines MG-63 and LM-8 in vitro and in vivo via perturbation of hyaluronan-rich pericellular matrix of the cells.
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The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in CancerTargeting ECM Disrupts Cancer ProgressionHyaluronan - a functional and structural sweet spot in the tissue microenvironmentInhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides.High-resolution microrheology in the pericellular matrix of prostate cancer cells.Identification of a novel chondroitin hydrolase in Caenorhabditis elegans.Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan.Silencing of CD44 gene expression in human 143-B osteosarcoma cells promotes metastasis of intratibial tumors in SCID miceRole of versican, hyaluronan and CD44 in ovarian cancer metastasis.Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharidesInhibition of hyaluronan retention by 4-methylumbelliferone suppresses osteosarcoma cells in vitro and lung metastasis in vivo.Glycol chitosan incorporated retinoic acid chlorochalcone (RACC) nanoparticles in the treatment of Osteosarcoma.Intracellular domain fragment of CD44 alters CD44 function in chondrocytes.Therapeutic targeting of hyaluronan in the tumor stroma.Targeting hyaluronic acid family for cancer chemoprevention and therapy.Sugars in the microenvironment: the sticky problem of HA turnover in tumors.Two novel functions of hyaluronidase-2 (Hyal2) are formation of the glycocalyx and control of CD44-ERM interactionsNo influence of exogenous hyaluronan on the behavior of human cancer cells or endothelial cell capillary formation.Different molecular weight hyaluronic acid effects on human macrophage interleukin 1β production.CD44 enhances tumor formation and lung metastasis in experimental osteosarcoma and is an additional predictor for poor patient outcome.Human Wharton's jelly stem cell conditioned medium and cell-free lysate inhibit human osteosarcoma and mammary carcinoma cell growth in vitro and in xenograft mice.Human umbilical cord Wharton's jelly stem cell (hWJSC) extracts inhibit cancer cell growth in vitro.Therapeutic potential of hyaluronan oligosaccharides for bone metastasis of breast cancer.Versican V1 isoform regulates cell-associated matrix formation and cell behavior differentially from aggrecan in Swarm rat chondrosarcoma cells.Inhibition of hyaluronan synthesis in breast cancer cells by 4-methylumbelliferone suppresses tumorigenicity in vitro and metastatic lesions of bone in vivo.Hyaluronan-CD44 Interactions in Cancer: Paradoxes and PossibilitiesAlginate Oligosaccharide DP5 Exhibits Antitumor Effects in Osteosarcoma Patients following Surgery.Effects of hyaluronic acid on mitochondrial function and mitochondria-driven apoptosis following oxidative stress in human chondrocytes.Hyaluronan synthesis inhibitor supplements the inhibitory effects of zoledronic acid on bone metastasis of lung cancer.Suppression of hyaluronan synthesis attenuates the tumorigenicity of low-grade chondrosarcoma.
P2860
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P2860
Hyaluronan oligosaccharides inhibit tumorigenicity of osteosarcoma cell lines MG-63 and LM-8 in vitro and in vivo via perturbation of hyaluronan-rich pericellular matrix of the cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Hyaluronan oligosaccharides in ...... icellular matrix of the cells.
@en
type
label
Hyaluronan oligosaccharides in ...... icellular matrix of the cells.
@en
prefLabel
Hyaluronan oligosaccharides in ...... icellular matrix of the cells.
@en
P2093
P2860
P1476
Hyaluronan oligosaccharides in ...... icellular matrix of the cells.
@en
P2093
Cheryl B Knudson
Kozo Hosono
Naoki Ishiguro
Takahiro Naruse
Warren Knudson
Yoshihiro Nishida
Yoshitaka Suzuki
P2860
P304
P356
10.2353/AJPATH.2007.060828
P407
P577
2007-07-01T00:00:00Z