Sliding of alkylating anticancer drugs along the minor groove of DNA: new insights on sequence selectivity
about
Dissociation of minor groove binders from DNA: insights from metadynamics simulations.DNA exit ramps are revealed in the binding landscapes obtained from simulations in helical coordinates.An omics perspective to the molecular mechanisms of anticancer metallo-drugs in the computational microscope era.Molecular motions in drug design: the coming age of the metadynamics method.From multiply active natural product to candidate drug? Antibacterial (and other) minor groove binders for DNA.Atomistic-level portrayal of drug-DNA Interplay: a history of courtships and meetings revealed by molecular simulations.Molecular recognition of DNA by ligands: roughness and complexity of the free energy profile.Thermodynamics of DNA: sensitizer recognition. Characterizing binding motifs with all-atom simulations.Decoding the conformation-linked functional properties of nucleic acids by the use of computational tools.
P2860
Q30484039-9828EAFB-8129-45BB-8080-A1846F0DE69DQ35559885-89EF93BC-935E-430F-ABC5-9E7AD0B53528Q36398911-DB9E1075-2881-42CE-8CC0-7657E3623278Q37843834-A2D5375D-2554-4020-847E-F62BB0231EEEQ38014897-D62573DE-4E00-4046-A62C-4B7D398DD926Q38237566-3E871D79-BE60-46EA-8A82-5F0379F7498BQ42934331-09F81374-95E5-4102-A90B-DA37F205E26DQ50214049-ACF8BD3C-0924-4B31-B89C-BF3B7C26D713Q53519380-9C3ADC30-93CE-4740-9AB3-4B44ABFA050C
P2860
Sliding of alkylating anticancer drugs along the minor groove of DNA: new insights on sequence selectivity
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Sliding of alkylating anticanc ...... sights on sequence selectivity
@en
type
label
Sliding of alkylating anticanc ...... sights on sequence selectivity
@en
prefLabel
Sliding of alkylating anticanc ...... sights on sequence selectivity
@en
P2093
P2860
P1433
P1476
Sliding of alkylating anticanc ...... sights on sequence selectivity
@en
P2093
Alessandra Magistrato
Attilio V Vargiu
Paolo Ruggerone
P2860
P304
P356
10.1529/BIOPHYSJ.107.113308
P407
P577
2008-01-01T00:00:00Z