Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling.
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Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunityAdvances in Autophagy Regulatory MechanismsSTING: infection, inflammation and cancerAutophagy signal transduction by ATG proteins: from hierarchies to networksTherapeutic targeting of autophagy in neurodegenerative and infectious diseasesCytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNAInnate immune pattern recognition: a cell biological perspectiveImmunologic manifestations of autophagyTRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STINGHepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M.RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanismsNew tricks for old dogs: countering antibiotic resistance in tuberculosis with host-directed therapeuticsCrosstalk Between Apoptosis and Autophagy: Environmental Genotoxins, Infection, and Innate Immunity.Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma.Pattern recognition receptors and autophagyMolecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STINGAutophagy in tuberculosiscGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs.IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMPUnabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells.The mechanism of double-stranded DNA sensing through the cGAS-STING pathwaySTING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells.Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.Deficiency in either 4E-BP1 or 4E-BP2 augments innate antiviral immune responsesInherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestationsPPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregationAutophagy, viruses, and intestinal immunityUV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity.Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.Central role of ULK1 in type I interferon signalingPosttranslational modification of autophagy-related proteins in macroautophagyMechanisms and pathways of innate immune activation and regulation in health and cancer.Modulation of the cGAS-STING DNA sensing pathway by gammaherpesvirusesSTING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease.cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein
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P2860
Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Cyclic dinucleotides trigger U ...... ained innate immune signaling.
@en
type
label
Cyclic dinucleotides trigger U ...... ained innate immune signaling.
@en
prefLabel
Cyclic dinucleotides trigger U ...... ained innate immune signaling.
@en
P2093
P2860
P1433
P1476
Cyclic dinucleotides trigger U ...... ained innate immune signaling.
@en
P2093
Glen N Barber
Hiroyasu Konno
Keiko Konno
P2860
P304
P356
10.1016/J.CELL.2013.09.049
P407
P577
2013-10-10T00:00:00Z