T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.
about
The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genesGeneration of pathogenic T(H)17 cells in the absence of TGF-β signallingAPC-derived cytokines and T cell polarization in autoimmune inflammationLinking obesity with type 2 diabetes: the role of T-betOrgan-specific and memory treg cells: specificity, development, function, and maintenanceNature and nurture in Foxp3(+) regulatory T cell development, stability, and functionAcute and persisting Th2-like immune response after fractionated colorectal gamma-irradiationDistinct populations of innate CD8+ T cells revealed in a CXCR3 reporter mouse.CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo.IL-4 attenuates Th1-associated chemokine expression and Th1 trafficking to inflamed tissues and limits pathogen clearance.Characterization of T-bet and eomes in peripheral human immune cellsT-bet, a Th1 transcription factor regulates the expression of Tim-3.IL-1β promotes the differentiation of polyfunctional human CCR6+CXCR3+ Th1/17 cells that are specific for pathogenic and commensal microbes.Inflammation programs self-reactive CD8+ T cells to acquire T-box-mediated effector function but does not prevent deletional toleranceLipopolysaccharide potentiates effector T cell accumulation into nonlymphoid tissues through TRIFOxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses.Recent thymic emigrants are biased against the T-helper type 1 and toward the T-helper type 2 effector lineage.Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection.CXCR3 in T cell function.T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells.Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.Alterations in regulatory T cells induced by specific oligosaccharides improve vaccine responsiveness in mice.The impact of KLF2 modulation on the transcriptional program and function of CD8 T cellsT-bet is critical for the development of acute graft-versus-host disease through controlling T cell differentiation and functionT-bet controls severity of hypersensitivity pneumonitisTailored immune responses: novel effector helper T cell subsets in protective immunity.Heteroclitic XBP1 peptides evoke tumor-specific memory cytotoxic T lymphocytes against breast cancer, colon cancer, and pancreatic cancer cells.Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis.More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases.IFNγ inhibits Th17 differentiation and function via Tbet-dependent and Tbet-independent mechanisms.Increased expression of peripheral blood leukocyte genes implicate CD14+ tissue macrophages in cellular intestine allograft rejection.Changes in histone acetylation and methylation that are important for persistent but not transient expression of CCR4 in human CD4+ T cells.Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity.Macrophage migration inhibitory factor promotes resistance to glucocorticoid treatment in EAE.Imbalance in distribution of functional autologous regulatory T cells in rheumatoid arthritisFunctionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells.T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17
P2860
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P2860
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.
@en
type
label
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.
@en
prefLabel
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.
@en
P2093
P2860
P1433
P1476
T-bet is required for optimal proinflammatory CD4+ T-cell trafficking
@en
P2093
Andrew H Lichtman
Brandon M Sullivan
F William Luscinskas
Hyeryun Choe
Laurie H Glimcher
Ravi M Rao
P2860
P304
P356
10.1182/BLOOD-2005-04-1393
P407
P577
2005-07-12T00:00:00Z