Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease
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Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 proteinCiliary Extracellular Vesicles: Txt Msg OrganellesRole of calcium in polycystic kidney disease: From signaling to pathologyRole of the Polycystins in Cell Migration, Polarity, and Tissue MorphogenesisA polycystin-centric view of cyst formation and disease: the polycystins revisitedPolycystin-1: a master regulator of intersecting cystic pathwaysWnt and planar cell polarity signaling in cystic renal diseasePolycystic liver diseases: advanced insights into the molecular mechanismsSystems biology of polycystic kidney disease: a critical reviewNedd9 restrains renal cystogenesis in Pkd1-/- miceThe native TRPP2-dependent channel of murine renal primary ciliaTrafficking to the primary cilium membrane.miRNAs in mammalian ureteric bud development.Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease.Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease.Cyst formation following disruption of intracellular calcium signalingEndothelial dysfunction and oxidative stress in polycystic kidney disease.Altered trafficking and stability of polycystins underlie polycystic kidney disease.Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.Inactivation of integrin-β1 prevents the development of polycystic kidney disease after the loss of polycystin-1.Electrical Signaling in Motile and Primary CiliaMolecular pathways and therapies in autosomal-dominant polycystic kidney diseaseAutosomal dominant polycystic kidney disease in children.Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney DiseaseGenetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk MouseThe Future of Polycystic Kidney Disease Research--As Seen By the 12 Kaplan Awardees.Human polycystin-2 transgene dose-dependently rescues ADPKD phenotypes in Pkd2 mutant mice.Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney DiseaseA TRPM4-dependent current in murine renal primary cilia.HIF Stabilization Weakens Primary Cilia.Regulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS siteAn age of enlightenment for cilia: The FASEB summer research conference on the "Biology of Cilia and Flagella"Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition.Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease.Primary cilia are not calcium-responsive mechanosensorsInhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney diseaseA cAMP and CREB-mediated feed-forward mechanism regulates GSK3β in polycystic kidney disease.Endothelial primary cilia inhibit atherosclerosis.mTOR controls kidney epithelia in health and disease.The primary cilium calcium channels and their role in flow sensing.
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P2860
Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Loss of cilia suppresses cyst ...... nant polycystic kidney disease
@en
type
label
Loss of cilia suppresses cyst ...... nant polycystic kidney disease
@en
prefLabel
Loss of cilia suppresses cyst ...... nant polycystic kidney disease
@en
P2093
P2860
P356
P1433
P1476
Loss of cilia suppresses cyst ...... nant polycystic kidney disease
@en
P2093
P2860
P2888
P304
P356
10.1038/NG.2715
P407
P577
2013-07-28T00:00:00Z
P5875
P6179
1036879228