Proteins in frozen solutions: evidence of ice-induced partial unfolding.
about
Long-term stability of a vaccine formulated with the amphipol-trapped major outer membrane protein from Chlamydia trachomatisEffect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization.A new approach to explore the impact of freeze-thaw cycling on protein structure: hydrogen/deuterium exchange mass spectrometry (HX-MS).Protein structure and interactions in the solid state studied by small-angle neutron scattering.Counteracting effects of thiocyanate and sucrose on chymotrypsinogen secondary structure and aggregation during freezing, drying, and rehydrationDistinct aggregation mechanisms of monoclonal antibody under thermal and freeze-thaw stresses revealed by hydrogen exchange.Freezing-induced perturbation of tertiary structure of a monoclonal antibodyPhage-displayed mimotopes elicit monoclonal antibodies specific for a malaria vaccine candidate.Tyrosine quenching of tryptophan phosphorescence in glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilusRole of protein cavities on unfolding volume change and on internal dynamics under pressure.A single freeze-thawing cycle for highly efficient solubilization of inclusion body proteins and its refolding into bioactive formMethods to study molecular mechanisms of the Neurospora circadian clockProtein stability during freezing: separation of stresses and mechanisms of protein stabilization.Freeze-drying of proteins from a sucrose-glycine excipient system: effect of formulation composition on the initial recovery of protein activity.Aggregates in monoclonal antibody manufacturing processes.Solid-state protein formulations.Ice premelting during differential scanning calorimetry.Perturbation of protein tertiary structure in frozen solutions revealed by 1-anilino-8-naphthalene sulfonate fluorescence.Microheterogeneity in frozen protein solutions.Freeze-thaw cycles as drivers of complex ribozyme assembly.Polyethylene glycol-induced precipitation of interferon alpha-2a followed by vacuum drying: development of a novel process for obtaining a dry, stable powderIn situ spectroscopic quantification of protein-ice interactions.Synergistic effects of surfactants and sugars on lipoplex stability during freeze-drying and rehydration.ANS fluorescence detects widespread perturbations of protein tertiary structure in ice.Examining the freezing process of an intermediate bulk containing an industrially relevant protein.Protein stability in ice.Tryptophan phosphorescence spectroscopy reveals that a domain in the NAD(H)-binding component (dI) of transhydrogenase from Rhodospirillum rubrum has an extremely rigid and conformationally homogeneous protein core.Assessment of degree of disorder (amorphicity) of lyophilized formulations of growth hormone using isothermal microcalorimetry.Beyond glass transitions: studying the highly viscous and elastic behavior of frozen protein formulations using low temperature rheology and its potential implications on protein stability.Immunogenicity of protein aggregates of a monoclonal antibody generated by forced shaking stress with siliconized and nonsiliconized syringes in BALB/c mice.Characteristics of proteinaceous additives in stabilizing enzymes during freeze-thawing and -drying.Structure engineering of filled protein microbeads to tailor release of oil droplets in gastric digestion.Impact of Buffer, Protein Concentration and Sucrose Addition on the Aggregation and Particle Formation during Freezing and Thawing.Frozen state storage instability of a monoclonal antibody: aggregation as a consequence of trehalose crystallization and protein unfolding
P2860
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P2860
Proteins in frozen solutions: evidence of ice-induced partial unfolding.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Proteins in frozen solutions: evidence of ice-induced partial unfolding.
@en
type
label
Proteins in frozen solutions: evidence of ice-induced partial unfolding.
@en
prefLabel
Proteins in frozen solutions: evidence of ice-induced partial unfolding.
@en
P2860
P1433
P1476
Proteins in frozen solutions: evidence of ice-induced partial unfolding.
@en
P2093
Gabellieri E
Strambini GB
P2860
P304
P356
10.1016/S0006-3495(96)79640-6
P407
P577
1996-02-01T00:00:00Z