HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice
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Induction of pluripotent protective immunity following immunisation with a chimeric vaccine against human cytomegalovirusMultiple viral ligands naturally presented by different class I molecules in transporter antigen processing-deficient vaccinia virus-infected cellsCross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccinationCytotoxic T cell immunity against telomerase reverse transcriptase in humansComparative vaccine studies in HLA-A2.1-transgenic mice reveal a clustered organization of epitopes presented in hepatitis C virus natural infection.Relation between viral fitness and immune escape within the hepatitis C virus proteaseHuman transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cellsDevelopment of a humanized HLA-A2.1/DP4 transgenic mouse model and the use of this model to map HLA-DP4-restricted epitopes of HBV envelope proteinQuantitating T cell cross-reactivity for unrelated peptide antigensConservation and diversity of influenza A H1N1 HLA-restricted T cell epitope candidates for epitope-based vaccines.Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinityIdentification and enhancement of HLA-A2.1-restricted CTL epitopes in a new human cancer antigen-POTE.The design and proof of concept for a CD8(+) T cell-based vaccine inducing cross-subtype protection against influenza A virus.Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses.Genetic immunization and comprehensive screening approaches in HLA-A2 transgenic mice lead to the identification of three novel epitopes in hepatitis C virus NS3 antigen.Immunization with a peptide containing MHC class I and II epitopes derived from the tumor antigen SIM2 induces an effective CD4 and CD8 T-cell responseIdentification of an HLA-A*0201-restricted T-cell epitope on the MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis, by MPT51 overlapping peptide screening.A novel liposome-based adjuvant CAF01 for induction of CD8(+) cytotoxic T-lymphocytes (CTL) to HIV-1 minimal CTL peptides in HLA-A*0201 transgenic mice.The mannosylated extracellular domain of Her2/neu produced in P. pastoris induces protective antitumor immunity.T cell-dependence of Lassa fever pathogenesis.Engineering chimeric human and mouse major histocompatibility complex (MHC) class I tetramers for the production of T-cell receptor (TCR) mimic antibodiesNatural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice.HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 monochain transgenic/H-2 class I null mice: novel versatile preclinical models of human T cell responses.Genetic vaccination strategies for enhanced cellular, humoral and mucosal immunity.H-2D(b-/-) mice are susceptible to persistent infection by Theiler's virusImmunogenicity of a human immunodeficiency virus (HIV) polytope vaccine containing multiple HLA A2 HIV CD8(+) cytotoxic T-cell epitopesIdentification of new MUC1 epitopes using HLA-transgenic animals: implication for immunomonitoring.Direct recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function.Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine.Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.Human leukocyte antigen (HLA) class I restricted epitope discovery in yellow fewer and dengue viruses: importance of HLA binding strengthRelationship between Poor Immunogenicity of HLA-A2-Restricted Peptide Epitopes and Paucity of Naïve CD8(+) T-Cell Precursors in HLA-A2-Transgenic Mice.A novel vascular targeting strategy for brain-derived endothelial cells using a TCR mimic antibody.Identification of a human telomerase reverse transcriptase peptide of low affinity for HLA A2.1 that induces cytotoxic T lymphocytes and mediates lysis of tumor cells.Tapasin modification on the intracellular epitope HBcAg18-27 enhances HBV-specific CTL immune response and inhibits hepatitis B virus replication in vivo.A novel minigene scaffold for therapeutic cancer vaccinesIdentification of vaccinia virus epitope-specific HLA-A*0201-restricted T cells and comparative analysis of smallpox vaccines.Reconstitution of huPBL-NSG mice with donor-matched dendritic cells enables antigen-specific T-cell activation.The extent of synaptic stripping of motoneurons after axotomy is not correlated to activation of surrounding glia or downregulation of postsynaptic adhesion molecules.Human CD1d-glycolipid tetramers generated by in vitro oxidative refolding chromatography
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HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
HLA-A2.1-restricted education ...... Db beta2m double knockout mice
@en
type
label
HLA-A2.1-restricted education ...... Db beta2m double knockout mice
@en
prefLabel
HLA-A2.1-restricted education ...... Db beta2m double knockout mice
@en
P2093
P2860
P356
P1476
HLA-A2.1-restricted education ...... Db beta2m double knockout mice
@en
P2093
P2860
P304
P356
10.1084/JEM.185.12.2043
P407
P577
1997-06-01T00:00:00Z