General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.
about
An in vitro evolved glmS ribozyme has the wild-type fold but loses coenzyme dependenceCrystal structure and mechanistic investigation of the twister ribozymeEvidence for the role of active site residues in the hairpin ribozyme from molecular simulations along the reaction path.Crystal structure of the Varkud satellite ribozyme.Phosphatase-inert glucosamine 6-phosphate mimics serve as actuators of the glmS riboswitch.Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulationsAssessment of metal-assisted nucleophile activation in the hepatitis delta virus ribozyme from molecular simulation and 3D-RISM.Heavy atom labeled nucleotides for measurement of kinetic isotope effectsA Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class.Intermolecular domain docking in the hairpin ribozyme: metal dependence, binding kinetics and catalysisMolecular Dynamics Study of Twister Ribozyme: Role of Mg(2+) Ions and the Hydrogen-Bonding Network in the Active Site.Nucleic acid reactivity: challenges for next-generation semiempirical quantum models.Thermodynamics and kinetics of RNA tertiary structure formation in the junctionless hairpin ribozyme.Structural and Biochemical Properties of Novel Self-Cleaving Ribozymes.The structure of a nucleolytic ribozyme that employs a catalytic metal ion.Mechanistic Debris Generated by Twister Ribozymes.Freeze-thaw cycles as drivers of complex ribozyme assembly.Non-canonical 3'-5' extension of RNA with prebiotically plausible ribonucleoside 2',3'-cyclic phosphatesCrystal structure of Pistol, a class of self-cleaving ribozyme.Synthesis and incorporation of the phosphoramidite derivative of 2'-O-photocaged 3'-s-thioguanosine into oligoribonucleotides: substrate for probing the mechanism of RNA catalysis.Pressure modulates the self-cleavage step of the hairpin ribozyme.Nucleic acids: function and potential for abiogenesis.Enzymatic synthesis of highly fluorescent 8-azapurine ribosides using a purine nucleoside phosphorylase reverse reaction: variable ribosylation sites.
P2860
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P2860
General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.
@en
type
label
General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.
@en
prefLabel
General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.
@en
P2093
P2860
P356
P1476
General acid-base catalysis mediated by nucleobases in the hairpin ribozyme
@en
P2093
David M J Lilley
Joseph A Piccirilli
Nan-Sheng Li
Timothy J Wilson
P2860
P304
16717-16724
P356
10.1021/JA3067429
P407
P577
2012-09-25T00:00:00Z