SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.
about
Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophagesSWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cellsSLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis.Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.Protein kinase C-η controls CTLA-4-mediated regulatory T cell function.IBP regulates epithelial-to-mesenchymal transition and the motility of breast cancer cells via Rac1, RhoA and Cdc42 signaling pathways.Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiationIRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells.Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activitySLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU).SWEF Proteins Distinctly Control Maintenance and Differentiation of Hematopoietic Stem Cells.DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies.SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.SLAT regulates CD8+ T cell clonal expansion in a Cdc42- and NFAT1-dependent mannerRho family GTPases and their regulators in lymphocytes.DEF6 expression in ovarian carcinoma correlates with poor patient survival.Rac GTPases play critical roles in early T-cell developmentRole of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis.IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway.SLAT negatively regulates RANKL-induced osteoclast differentiation.Ectopically expressed IBP promotes cell proliferation in oral squamous cell carcinoma.Identification of a Novel Alternatively Spliced Form of Inflammatory Regulator SWAP-70-Like Adapter of T Cells.Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells.Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption.
P2860
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P2860
SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.
@en
type
label
SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.
@en
prefLabel
SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.
@en
P2093
P2860
P356
P1476
SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+/NFAT signaling.
@en
P2093
Amnon Altman
Ann J Canonigo Balancio
Carl De Trez
Céline Charvet
Michael Croft
Stéphane Bécart
Yoshihiko Tanaka
P2860
P304
P356
10.1172/JCI31640
P407
P577
2007-08-01T00:00:00Z