Amino acid availability regulates p70 S6 kinase and multiple translation factors.
about
Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinaseThe regulation of protein synthesis and translation factors by CD3 and CD28 in human primary T lymphocytes.Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycinDistinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.Signaling by target of rapamycin proteins in cell growth controlInsulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin.Evidence that the dephosphorylation of Ser(535) in the epsilon-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulinRegulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repressionA novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulinRegulation of 4E-BP1 phosphorylation: a novel two-step mechanismmTOR: from growth signal integration to cancer, diabetes and ageingThe role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistanceConserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signalingAmino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TORAmino acids and mTORC1: from lysosomes to diseaseNutrient-sensing mechanisms across evolutionRegulation of mTORC1 by amino acidsThe expanding role of mTOR in cancer cell growth and proliferationThe TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine.Amino acid-induced stimulation of translation initiation in rat skeletal muscleBimodal activation of acetyl-CoA carboxylase by glutamateCellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factorsRegulation of ribosomal S6 kinase 2 by mammalian target of rapamycinGlucose exerts a permissive effect on the regulation of the initiation factor 4E binding protein 4E-BP1Amino acids regulate skeletal muscle PHAS-I and p70 S6-kinase phosphorylation independently of insulinInsulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activityA pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell deathBidirectional transport of amino acids regulates mTOR and autophagyDexamethasone inhibits the stimulation of muscle protein synthesis and PHAS-I and p70 S6-kinase phosphorylation.Human protein metabolism: its measurement and regulation.Cell growth control: little eukaryotes make big contributions.Acute regulation of translation initiation by gonadotropin-releasing hormone in the gonadotrope cell line LbetaT2Glucocorticoids modulate amino acid-induced translation initiation in human skeletal muscle.PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways.Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylationThe actions of exogenous leucine on mTOR signalling and amino acid transporters in human myotubes.Regulation of glycogen synthesis by amino acids in cultured human muscle cells.Signal transduction pathways that regulate eukaryotic protein synthesis.
P2860
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P2860
Amino acid availability regulates p70 S6 kinase and multiple translation factors.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Amino acid availability regulates p70 S6 kinase and multiple translation factors.
@en
type
label
Amino acid availability regulates p70 S6 kinase and multiple translation factors.
@en
prefLabel
Amino acid availability regulates p70 S6 kinase and multiple translation factors.
@en
P2093
P2860
P356
P1433
P1476
Amino acid availability regulates p70 S6 kinase and multiple translation factors.
@en
P2093
P2860
P304
P356
10.1042/BJ3340261
P407
P478
334 ( Pt 1)
P577
1998-08-01T00:00:00Z