ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis. - Wikidata - awgldk - TriplyDB

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.

http://www.wikidata.org/entity/Q41921041

about

Sphingolipids in High Fat Diet and Obesity-Related Diseases Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis.Cathepsin D regulates lipid metabolism in murine steatohepatitis.Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDL Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells.Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy.Glycosphingolipids and cell death: one aim, many ways Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis.Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin.Mitochondrial cholesterol accumulation in alcoholic liver disease: Role of ASMase and endoplasmic reticulum stress.The emerging role of acid sphingomyelinase in autophagy.The role of lysosome in cell death regulation.Modulation of Neuroinflammation in the Central Nervous System: Role of Chemokines and Sphingolipids.Lipids, lysosomes, and autophagy.Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells.Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease.Dietary and Endogenous Sphingolipid Metabolism in Chronic Inflammation.Lipophagy prevents activity-dependent neurodegeneration due to dihydroceramide accumulation in vivo.Tricyclic antidepressant use and the risk of fibrosis progression in hepatitis C-infected persons: Results from ERCHIVES.Cholesterol and bile acid-mediated regulation of autophagy in fatty liver diseases and atherosclerosis.The Biological Clock: A Pivotal Hub in Non-alcoholic Fatty Liver Disease Pathogenesis.Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide.

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P2860

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.

http://www.wikidata.org/entity/Q41921041

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

ASMase regulates autophagy and ...... non-alcoholic steatohepatitis.

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ASMase regulates autophagy and ...... non-alcoholic steatohepatitis.

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ASMase regulates autophagy and ...... non-alcoholic steatohepatitis.

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P356

J.JHEP.2014.06.009

P1433

Journal of Hepatology

P1476

ASMase regulates autophagy and ...... non-alcoholic steatohepatitis.

@en

P2093

Alma M Astudillo

http://www.w3.org/2001/XMLSchema#string

Anna Baulies

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Anna Fernandez

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Carmen García-Ruiz

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Christian Trautwein

http://www.w3.org/2001/XMLSchema#string

Hanna Appelqvist

http://www.w3.org/2001/XMLSchema#string

Ina Bergheim

http://www.w3.org/2001/XMLSchema#string

James C Paton

http://www.w3.org/2001/XMLSchema#string

Laura Martínez

http://www.w3.org/2001/XMLSchema#string

Mark J Czaja

http://www.w3.org/2001/XMLSchema#string

P2860

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide

Autophagy regulates lipid metabolism

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

Defective TNF-alpha-mediated hepatocellular apoptosis and liver damage in acidic sphingomyelinase knockout mice.

Autophagy deficiency by hepatic FIP200 deletion uncouples steatosis from liver injury in NAFLD.

Ceramide in the eukaryotic stress response.

Interactions between metabolism and intracellular distribution of cholesterol and sphingomyelin.

P304

1126-1134

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scholarly article

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10.1016/J.JHEP.2014.06.009

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5

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61

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José C Fernández-Checa

Jesús Balsinde

Sophie Lotersztajn

Sophie Lotersztajn

Adrienne W Paton

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2014-06-16T00:00:00Z

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263321211

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24946279

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Steatohepatitis

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4203709

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