Role of elongation and secondary pathways in S6 amyloid fibril growth.
about
The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranesInteraction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aβ42) aggregates leads to sub-stoichiometric inhibition of amyloid formationSolution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregationPolymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple pathways with different oligomeric intermediates.The physical chemistry of the amyloid phenomenon: thermodynamics and kinetics of filamentous protein aggregation.The native state of prion protein (PrP) directly inhibits formation of PrP-amyloid fibrils in vitro.Glycerol inhibits the primary pathways and transforms the secondary pathway of insulin aggregation.Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification.Critical Influence of Cosolutes and Surfaces on the Assembly of Serpin-Derived Amyloid Fibrils.Imaging Aβ(1-42) fibril elongation reveals strongly polarised growth and growth incompetent states.Strong interactions with polyethylenimine-coated human serum albumin nanoparticles (PEI-HSA NPs) alter α-synuclein conformation and aggregation kinetics.
P2860
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P2860
Role of elongation and secondary pathways in S6 amyloid fibril growth.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Role of elongation and secondary pathways in S6 amyloid fibril growth.
@en
type
label
Role of elongation and secondary pathways in S6 amyloid fibril growth.
@en
prefLabel
Role of elongation and secondary pathways in S6 amyloid fibril growth.
@en
P2093
P2860
P50
P1433
P1476
Role of elongation and secondary pathways in S6 amyloid fibril growth
@en
P2093
Christopher M Dobson
Nikolai Lorenzen
Samuel I A Cohen
Søren B Nielsen
Therese W Herling
P2860
P304
P356
10.1016/J.BPJ.2012.03.047
P407
P577
2012-05-01T00:00:00Z