bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.
about
Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosisGerminal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activationEvidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxesWT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosisThe intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/MMultiple Bcl-2 family members demonstrate selective dimerizations with BaxExpression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic miceThe Bcl-2 apoptotic switch in cancer development and therapyBcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapyProtein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosisFollicular lymphoma-like B cells in healthy individuals: a novel intermediate step in early lymphomagenesisCancer Hallmarks, Biomarkers and Breast Cancer Molecular SubtypesPotential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?Targeting the Bcl-2 family for cancer therapyBAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial poreThe BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer TherapeuticsMolecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11Targeting -Herpesvirus 68 Bcl-2-mediated Down-regulation of AutophagyIt's a cell-eat-cell world: autophagy and phagocytosis.Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agentsIsotype-switched follicular lymphoma displays dissociation between activation-induced cytidine deaminase expression and somatic hypermutationLight induced apoptosis is accelerated in transgenic retina overexpressing human EAT/mcl-1, an anti-apoptotic bcl-2 related geneSplenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levelsDevelopmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytesEssential role of BAX,BAK in B cell homeostasis and prevention of autoimmune diseaseCitrate synthase expression affects tumor phenotype and drug resistance in human ovarian carcinomaDeletion of AU-rich elements within the Bcl2 3'UTR reduces protein expression and B cell survival in vivoThymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphomaBCMA is essential for the survival of long-lived bone marrow plasma cellsTargeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopeniaTransgenic models of lymphoid neoplasia and development of a pan-hematopoietic vectorInvolvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapyMulticolour fluorescence in situ hybridization analysis of t(14;18)-positive follicular lymphoma and correlation with gene expression data and clinical outcome.Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray.Genetic synthetic lethality screen at the single gene level in cultured human cells.Clonal expansion in follicular lymphoma occurs subsequent to antigenic selection.Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency.Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity.
P2860
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P2860
bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
bcl-2-immunoglobulin transgeni ...... ollicular lymphoproliferation.
@en
type
label
bcl-2-immunoglobulin transgeni ...... ollicular lymphoproliferation.
@en
prefLabel
bcl-2-immunoglobulin transgeni ...... ollicular lymphoproliferation.
@en
P2093
P1433
P1476
bcl-2-immunoglobulin transgeni ...... ollicular lymphoproliferation.
@en
P2093
Korsmeyer SJ
McDonnell TJ
McKearn JP
P356
10.1016/0092-8674(89)90174-8
P407
P577
1989-04-01T00:00:00Z