Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome.
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Down syndrome: searching for the genetic culpritsEmerging pharmacotherapies for neurodevelopmental disordersOlig1 and Olig2 triplication causes developmental brain defects in Down syndromeThe GIRK1 brain variant GIRK1d and its functional impact on heteromultimeric GIRK channels.Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome.Generation of a panel of antibodies against proteins encoded on human chromosome 21.Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brainDown syndrome--recent progress and future prospects.Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndromeTrisomy of the G protein-coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions, and synaptic plasticity in mice.Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic MiceFrom abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome.Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists.Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome.Aneuploidy: from a physiological mechanism of variance to Down syndrome.The GABAergic Hypothesis for Cognitive Disabilities in Down SyndromeSTDP and Mental Retardation: Dysregulation of Dendritic Excitability in Fragile X Syndrome.Is it possible to improve neurodevelopmental abnormalities in Down syndrome?Autism spectrum disorders: the quest for genetic syndromes.New insights into the therapeutic potential of Girk channels.GABAergic dysfunction in pediatric neuro-developmental disorders.Altered intrinsic and network properties of neocortical neurons in the Ts65Dn mouse model of Down syndromeGABAergic hyperinnervation of dentate granule cells in the Ts65Dn mouse model of down syndrome: Exploring the role of App.The GIRK2 subunit is involved in IS-like seizures induced by GABA(B) receptor agonists.G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channel Activation by the p75 Neurotrophin Receptor Is Required for Amyloid β Toxicity.Infantile spasms and Down syndrome: a new animal model.Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships.Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome.Infantile spasms in down syndrome: Rescue by knockdown of the GIRK2 channel.Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome.
P2860
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P2860
Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Abnormal expression of the G-p ...... use: a model of Down syndrome.
@en
type
label
Abnormal expression of the G-p ...... use: a model of Down syndrome.
@en
prefLabel
Abnormal expression of the G-p ...... use: a model of Down syndrome.
@en
P2093
P2860
P356
P1476
Abnormal expression of the G-p ...... use: a model of Down syndrome.
@en
P2093
Chie Harashima
David M Jacobowitz
Jassir Witta
Richard J Siarey
Rosemary C Borke
Tyler K Best
Zygmunt Galdzicki
P2860
P304
P356
10.1002/CNE.20844
P407
P577
2006-02-01T00:00:00Z