Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1. - Wikidata - awgldk - TriplyDB

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

http://www.wikidata.org/entity/Q41983843

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CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation Fundamentals of cancer metabolism Anticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effect The mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trials The role of the ribosome in the regulation of longevity and lifespan extension Energy disruptors: rising stars in anticancer therapy?Oncogenes strike a balance between cellular growth and homeostasis Amino acid management in cancer Integrating canonical and metabolic signalling programmes in the regulation of T cell responses mTORC1 signaling activates NRF1 to increase cellular proteasome levels The role of tumor suppressor p53 in the antioxidant defense and metabolism The expanding role of mTOR in cancer cell growth and proliferation Nutrient regulation of the mTOR complex 1 signaling pathway Dynamic phosphoproteomics reveals TORC1-dependent regulation of yeast nucleotide and amino acid biosynthesis.Mourning Dr. Alfred G. Knudson: the two-hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complex Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives Adipose tissue dysfunction and its effects on tumor metabolism mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2)Where is mTOR and what is it doing there?Lignocellulose depolymerization occurs via an environmentally adapted metabolic cascades in the wood-rotting basidiomycete Phanerochaete chrysosporium Complementary substrate-selectivity of metabolic adaptive convergence in the lignocellulolytic performance by Dichomitus squalens Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated meta-analysis Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance.The role of target of rapamycin signaling networks in plant growth and metabolism.From Krebs to clinic: glutamine metabolism to cancer therapy.The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma.Akt phosphorylation and regulation of transketolase is a nodal point for amino acid control of purine synthesis Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma.Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism.Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21.Targeting mTOR dependency in pancreatic cancer Targeting mTORC1-mediated metabolic addiction overcomes fludarabine resistance in malignant B cells.The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation Sestrins orchestrate cellular metabolism to attenuate aging.Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma.Activation of diverse signalling pathways by oncogenic PIK3CA mutations.Inhibition of p70 S6 kinase (S6K1) activity by A77 1726 and its effect on cell proliferation and cell cycle progress.

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P2860

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

http://www.wikidata.org/entity/Q41983843

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

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Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

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Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

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Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

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Brendan D Manning

http://www.w3.org/2001/XMLSchema#string

Issam Ben-Sahra

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Jessica J Howell

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John M Asara

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P2860

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

Phosphorylation and activation of hamster carbamyl phosphate synthetase II by cAMP-dependent protein kinase. A novel mechanism for regulation of pyrimidine nucleotide biosynthesis

mTOR signaling in growth control and disease

Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

Regulation of carbamoyl phosphate synthetase by MAP kinase

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

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10.1126/SCIENCE.1228792

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