Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.
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Hypoxia induces PDK4 gene expression through induction of the orphan nuclear receptor ERRγRole of Transcription Factors in Steatohepatitis and Hypertension after Ethanol: The Epicenter of MetabolismHypoxia-inducible factors as molecular targets for liver diseasesThe Crosstalk between Hypoxia and Innate Immunity in the Development of Obesity-Related Nonalcoholic Fatty Liver DiseaseLeaky gut and the liver: a role for bacterial translocation in nonalcoholic steatohepatitisAlcoholic liver disease: pathogenesis and new therapeutic targets.Leveraging oxidative stress questions in vivo: Implications and limitationsGut Microbiota and Host Reaction in Liver DiseasesHypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease.Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice.Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis.Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation.Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in miceMetabolic consequences of high-fat diet are attenuated by suppression of HIF-1α.Pathogenesis of alcoholic liver disease: role of oxidative metabolism.microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis.A novel antioxidant multitarget iron chelator M30 protects hepatocytes against ethanol-induced injuryAcute ethanol causes hepatic mitochondrial depolarization in mice: role of ethanol metabolism.Reduction of oxidative stress attenuates lipoapoptosis exacerbated by hypoxia in human hepatocytes.Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice.Hepatocyte-specific deletion of ARNT (aryl hydrocarbon Receptor Nuclear Translocator) results in altered fibrotic gene expression in the thioacetamide model of liver injury.MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis.Chenodeoxycholic Acid Reduces Hypoxia Inducible Factor-1α Protein and Its Target Genes.Suppression of silent information regulator 1 activity in noncancerous tissues of hepatocellular carcinoma: Possible association with non-B non-C hepatitis pathogenesis.Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1α-dependent manner by modulating macrophage phenotype in miceNew Approaches for Studying Alcoholic Liver DiseaseAlcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice.Simulating sleep apnea by exposure to intermittent hypoxia induces inflammation in the lung and liver.Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expressionAlcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1α activation.Inflammation in alcoholic liver disease.The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis.Linking Pathogenic Mechanisms of Alcoholic Liver Disease With Clinical Phenotypes.Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivoMouse model of chronic and binge ethanol feeding (the NIAAA model)Reduction of hepatic fibrosis by overexpression of von Hippel-Lindau protein in experimental models of chronic liver diseaseMetabolic syndrome and mitochondrial dysfunction: insights from preclinical studies with a mitochondrially targeted antioxidant.Chromatin as an oxygen sensor and active player in the hypoxia response.Hypoxia and hypoxia inducible factors: diverse roles in liver diseases.Hypoxia and fatty liver.
P2860
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P2860
Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Hepatocyte-specific hypoxia-in ...... hol-induced steatosis in mice.
@en
type
label
Hepatocyte-specific hypoxia-in ...... hol-induced steatosis in mice.
@en
prefLabel
Hepatocyte-specific hypoxia-in ...... hol-induced steatosis in mice.
@en
P2093
P2860
P356
P1433
P1476
Hepatocyte-specific hypoxia-in ...... ohol-induced steatosis in mice
@en
P2093
Bharath Nath
Christian Mueller
Donna Catalano
Gyongyi Szabo
Ivan Levin
Jan Petrasek
Karen Kodys
Timea Csak
P2860
P304
P356
10.1002/HEP.24256
P407
P577
2011-05-01T00:00:00Z