Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol.
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Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemiaTherapeutic options for management of endometrial hyperplasiaProteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2{middle dot}DNA and Top2{middle dot}RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)Plant-Based and Plant-Rich Diet Patterns during Gestation: Beneficial Effects and Possible ShortcomingsInhibitors of human immunodeficiency virus integraseEstrogen receptor α and aryl hydrocarbon receptor independent growth inhibitory effects of aminoflavone in breast cancer cells.Genistein directly inhibits native and recombinant NMDA receptors.Integrating traditional medicine into modern inflammatory diseases care: multitargeting by Rhus verniciflua StokesRecent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance.An alternative mode of action of endocrine-disrupting chemicals and chemoprevention.Genistein, a dietary-derived inhibitor of in vitro angiogenesisDietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not.Induction of topoisomerase II-mediated DNA cleavage by the plant naphthoquinones plumbagin and shikoninPhytoestrogens: perpetrators or protectors?Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis, and estrogenic outcomes in healthy postmenopausal women: a phase I clinical trialModulation of radiation-induced and mitomycin C-induced chromosome damage by apigenin in human lymphocytes in vitro.Genistein potentiates the effect of 17-beta estradiol on human hepatocellular carcinoma cell lineEstrogen treatment induces MLL aberrations in human lymphoblastoid cells.Isoflavones: estrogenic activity, biological effect and bioavailability.Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I.The dietary anticancer agent ellagic acid is a potent inhibitor of DNA topoisomerases in vitro.C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis.Antioxidants and hormone-mediated health benefits of whole grains.Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors.Genistein-induced G2-M arrest, p21WAF1 upregulation, and apoptosis in a non-small-cell lung cancer cell line.Phyto-oestrogens and Western diseases.Genistein augments cyclic adenosine 3'5'-monophosphate(cAMP) accumulation and insulin release in MIN6 cells.Natural-product inhibitors of human DNA ligase I.Antimicrobial and antiurease activities of newly synthesized morpholine derivatives containing an azole nucleus.Comparative analysis of topoisomerase IB inhibition and DNA intercalation by flavonoids and similar compounds: structural determinates of activity.Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives.Designing and testing of an effective oil-in-water microemulsion drug delivery system for in vivo application.Risk assessment for peri- and post-menopausal women taking food supplements containing isolated isoflavones
P2860
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P2860
Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Induction of mammalian topoiso ...... vonoids, genistein and orobol.
@en
type
label
Induction of mammalian topoiso ...... vonoids, genistein and orobol.
@en
prefLabel
Induction of mammalian topoiso ...... vonoids, genistein and orobol.
@en
P2093
P1476
Induction of mammalian topoiso ...... vonoids, genistein and orobol.
@en
P2093
P304
P356
10.1016/0006-2952(90)90153-C
P407
P577
1990-02-01T00:00:00Z