Conversion of the 2 Cl(-)/1 H+ antiporter ClC-5 in a NO3(-)/H+ antiporter by a single point mutation.
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Thyroid iodide efflux: a team effort?Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycleThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsThe ClC-3 Cl-/H+ antiporter becomes uncoupled at low extracellular pHRole of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation.CLC channels and transporters: proteins with borderline personalities.Proton block of the CLC-5 Cl-/H+ exchanger.Basis of substrate binding and conservation of selectivity in the CLC family of channels and transportersDeterminants of coupled transport and uncoupled current by the electrogenic SLC26 transporters.Physiology and pathophysiology of ClC-K/barttin channels.On the mechanism of gating charge movement of ClC-5, a human Cl(-)/H(+) antiporterSynergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.Molecular Basis for Differential Anion Binding and Proton Coupling in the Cl(-)/H(+) Exchanger ClC-ec1A single point mutation reveals gating of the human ClC-5 Cl-/H+ antiporter.Water access points and hydration pathways in CLC H+/Cl- transporters.CLC transport proteins in plants.Vacuolar ion channels: Roles in plant nutrition and signalling.Cell biology and physiology of CLC chloride channels and transporters.A tale of two CLCs: biophysical insights toward understanding ClC-5 and ClC-7 function in endosomes and lysosomes.Structure and gating of CLC channels and exchangers.A pure chloride channel mutant of CLC-5 causes Dent's disease via insufficient V-ATPase activation.Functional coupling of V-ATPase and CLC-5.ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies.Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger.Direct endosomal acidification by the outwardly rectifying CLC-5 Cl(-)/H(+) exchanger.Extracellular determinants of anion discrimination of the Cl-/H+ antiporter protein CLC-5.Alkaline pH block of CLC-K kidney chloride channels mediated by a pore lysine residue.Structure of a CLC chloride ion channel by cryo-electron microscopyClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity.Probing the conformation of a conserved glutamic acid within the Cl- pathway of a CLC H+/Cl- exchanger.The late endosomal ClC-6 mediates proton/chloride countertransport in heterologous plasma membrane expression.Glutamate 268 regulates transport probability of the anion/proton exchanger ClC-5.Functional coupling of chloride-proton exchanger ClC-5 to gastric H+,K+-ATPaseA9C sensitive Cl⁻-accumulation in A. thaliana root cells during salt stress is controlled by internal and external calcium.A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.Common gating of both CLC transporter subunits underlies voltage-dependent activation of the 2Cl-/1H+ exchanger ClC-7/Ostm1.Intracellular regulation of human ClC-5 by adenine nucleotides.Anion- and proton-dependent gating of ClC-4 anion/proton transporter under uncoupling conditions.Molecular Pharmacology of Kidney and Inner Ear CLC-K Chloride Channels.Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis.
P2860
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P2860
Conversion of the 2 Cl(-)/1 H+ antiporter ClC-5 in a NO3(-)/H+ antiporter by a single point mutation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Conversion of the 2 Cl
@nl
Conversion of the 2 Cl(-)/1 H+ ...... er by a single point mutation.
@en
type
label
Conversion of the 2 Cl
@nl
Conversion of the 2 Cl(-)/1 H+ ...... er by a single point mutation.
@en
prefLabel
Conversion of the 2 Cl
@nl
Conversion of the 2 Cl(-)/1 H+ ...... er by a single point mutation.
@en
P2860
P356
P1433
P1476
Conversion of the 2 Cl(-)/1 H+ ...... er by a single point mutation.
@en
P2093
Giovanni Zifarelli
P2860
P304
P356
10.1038/EMBOJ.2008.284
P407
P577
2009-01-08T00:00:00Z