Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin: high-resolution mechanistic implications for channel regulation by Ca2+
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Ca2+-dependent modulation of voltage-gated Ca2+ channelsMultiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerizationSolution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5Calmodulin regulation (calmodulation) of voltage-gated calcium channelsTowards a Unified Theory of Calmodulin Regulation (Calmodulation) of Voltage-Gated Calcium and Sodium ChannelsThe calmodulin-binding, short linear motif, NSCaTE is conserved in L-type channel ancestors of vertebrate Cav1.2 and Cav1.3 channelsStructures of CaV2 Ca2+/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and FacilitationCrystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+* calmodulinsDeterminants in CaV1 Channels That Regulate the Ca2+ Sensitivity of Bound CalmodulinStructural Studies of Soybean Calmodulin Isoform 4 Bound to the Calmodulin-binding Domain of Tobacco Mitogen-activated Protein Kinase Phosphatase-1 Provide Insights into a Sequential Target Binding ModeStructural Basis for the Differential Effects of CaBP1 and Calmodulin on CaV1.2 Calcium-Dependent InactivationStructural and Energetic Determinants of Apo Calmodulin Binding to the IQ Motif of the NaV1.2 Voltage-Dependent Sodium ChannelStructural basis for the regulation of L-type voltage-gated calcium channels: interactions between the N-terminal cytoplasmic domain and Ca2+-calmodulinStructural Basis for Calmodulin as a Dynamic Calcium SensorAllosteric mechanism of water-channel gating by Ca2+–calmodulinCompensatory regulation of Cav2.1 Ca2+ channels in cerebellar Purkinje neurons lacking parvalbumin and calbindin D-28k.Reduction of CaV channel activities by Ca2+-CaM: inactivation or deactivation?Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation.Continuously tunable Ca(2+) regulation of RNA-edited CaV1.3 channels.Calmodulin overexpression does not alter Cav1.2 function or oligomerization state.Structural insights into neuronal K+ channel-calmodulin complexes.Post-transcriptional modifications and "Calmodulation" of voltage-gated calcium channel function: Reflections by two collaborators of David T YueCompetitive and non-competitive regulation of calcium-dependent inactivation in CaV1.2 L-type Ca2+ channels by calmodulin and Ca2+-binding protein 1Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacologyEngineering proteins for custom inhibition of Ca(V) channels.Cooperative and acute inhibition by multiple C-terminal motifs of L-type Ca2+ channels.Calcium-dependent stoichiometries of the KCa2.2 (SK) intracellular domain/calmodulin complex in solution.Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin.Seeing the forest through the trees: towards a unified view on physiological calcium regulation of voltage-gated sodium channels.Structural analysis of calmodulin binding to ion channels demonstrates the role of its plasticity in regulation.The many structural faces of calmodulin: a multitasking molecular jackknife.Ion channel engineering: perspectives and strategies.Sense and specificity in neuronal calcium signalling.A rendezvous with the queen of ion channels: Three decades of ion channel research by David T Yue and his Calcium Signals Laboratory.Calmodulin and Ca(2+) control of voltage gated Na(+) channels.The Mechanisms and Functions of Synaptic Facilitation.NMR studies of the interaction of calmodulin with IQ motif peptides.Interactions between N and C termini of α1C subunit regulate inactivation of CaV1.2 L-type Ca(2+) channel.Calmodulin is a functional regulator of Cav1.4 L-type Ca2+ channelsThe amino-terminus of high voltage activated calcium channels: CaM you or can't you?
P2860
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P2860
Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin: high-resolution mechanistic implications for channel regulation by Ca2+
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Crystal structure of the CaV2 ...... for channel regulation by Ca2+
@en
Crystal structure of the CaV2 ...... for channel regulation by Ca2+
@nl
type
label
Crystal structure of the CaV2 ...... for channel regulation by Ca2+
@en
Crystal structure of the CaV2 ...... for channel regulation by Ca2+
@nl
prefLabel
Crystal structure of the CaV2 ...... for channel regulation by Ca2+
@en
Crystal structure of the CaV2 ...... for channel regulation by Ca2+
@nl
P2093
P2860
P1433
P1476
Crystal structure of the CaV2 ...... for channel regulation by Ca2+
@en
P2093
Craig W Vander Kooi
Daniel J Leahy
David T Yue
Masayuki X Mori
P2860
P304
P356
10.1016/J.STR.2008.01.011
P577
2008-04-01T00:00:00Z