The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis. - Wikidata - awgldk - TriplyDB

The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis.

The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis.

http://www.wikidata.org/entity/Q42018928

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Endothelial cells in dengue hemorrhagic fever Angiopoietin-1 requires oxidant signaling through p47phox to promote endothelial barrier defense Cellular and Molecular Mechanisms of AKI.The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury.Imaging in sepsis-associated encephalopathy--insights and opportunities.Effect of salidroside on lung injury by upregulating peroxisome proliferator-activated receptor γ expression in septic rats.A high angiopoietin-2/angiopoietin-1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia A tale of two ligands: angiopoietins, the endothelium, and outcomes Angiopoietin-2 is a potential mediator of endothelial barrier dysfunction following cardiopulmonary bypass.Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model.The angiopoietin-Tie2 signaling axis in the vascular leakage of systemic inflammation Vasculotide reduces endothelial permeability and tumor cell extravasation in the absence of binding to or agonistic activation of Tie2.Biomarkers of Endothelial Activation Are Associated with Poor Outcome in Critical Illness.Vasculotide, an Angiopoietin-1 mimetic, ameliorates several features of experimental atopic dermatitis-like disease.Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited.Fixing the leak: targeting the vascular endothelium in sepsis.Angiopoietin-1 variant reduces LPS-induced microvascular dysfunction in a murine model of sepsis Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis*Pharmacological Tie2 activation in kidney transplantation.Role of angiopoietin/tie2 in critical illness: promising biomarker, disease mediator, and therapeutic target?A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis.Cellular adaptive changes in AKI: mitigating renal hypoxic injury.Dysregulation of the angiopoietin-Tie-2 axis in sepsis and ARDS.Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction.Phosphatases and kinases as regulators of the endothelial barrier function.Dynamics of pulmonary endothelial barrier function in acute inflammation: mechanisms and therapeutic perspectives.Similarities and differences in the regulation of leukocyte extravasation and vascular permeability.Endothelial barrier dysfunction in septic shock.Beyond single-nucleotide polymorphisms: genetics, genomics, and other 'omic approaches to acute respiratory distress syndrome Angiopoietin-2: a multifaceted cytokine that functions in both angiogenesis and inflammation.Renal endothelial injury and microvascular dysfunction in acute kidney injury.Novel relationships between oxidative stress and angiogenesis-related factors in sepsis: New biomarkers and therapies.Endothelial glycocalyx breakdown is mediated by angiopoietin-2.Angiopoietins and Tie2 in vascular inflammation.Amelioration of sepsis by TIE2 activation-induced vascular protection.Characterization of changes in plasma and tissue oxylipin levels in LPS and CLP induced murine sepsis.Is nosocomial infection really the major cause of death in sepsis?von Willebrand factor and angiopoietin-2: toward an acute lung injury endothelial endophenotype?

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The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis.

http://www.wikidata.org/entity/Q42018928

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

The synthetic tie2 agonist pep ...... ty in murine abdominal sepsis.

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The synthetic tie2 agonist pep ...... ty in murine abdominal sepsis.

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type

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The synthetic tie2 agonist pep ...... ty in murine abdominal sepsis.

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The synthetic tie2 agonist pep ...... ty in murine abdominal sepsis.

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The synthetic tie2 agonist pep ...... ty in murine abdominal sepsis.

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The synthetic tie2 agonist pep ...... ty in murine abdominal sepsis.

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The synthetic tie2 agonist pep ...... ty in murine abdominal sepsis.

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Clemens L Bockmeyer

http://www.w3.org/2001/XMLSchema#string

Daniel J Dumont

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Faikah Gueler

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Hermann Pavenstadt

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Joon-Keun Park

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Nelli Shushakova

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Paul Van Slyke

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Philipp Kumpers

http://www.w3.org/2001/XMLSchema#string

Samir M Parikh

http://www.w3.org/2001/XMLSchema#string

Sascha David

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P2860

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo

Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor.

Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome

Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury.

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