Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives - Wikidata - awgldk - TriplyDB

Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives

Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives

http://www.wikidata.org/entity/Q42023392

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Interactions between CYP3A4 and Dietary Polyphenols Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic Metabolism Comparison of the inhibitory profiles of itraconazole and cimetidine in cytochrome P450 3A4 genetic variants Hop (Humulus lupulus L.) extract and 6-prenylnaringenin induce P450 1A1 catalyzed estrogen 2-hydroxylation Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity.Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.Effects of rhamnocitrin 4-β-D-galactopyranoside, isolated from Astragalus hamosus on toxicity models in vitro.Cytochrome P450 family 1 inhibitors and structure-activity relationships.Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1.Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds Polycyclic aromatic hydrocarbons: from metabolism to lung cancer.7-Ethynylcoumarins: selective inhibitors of human cytochrome P450s 1A1 and 1A2.In Silico Predictions of Drug - Drug Interactions Caused by CYP1A2, 2C9 and 3A4 Inhibition - a Comparative Study of Virtual Screening Performance.A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2 Identification and Molecular Analysis of Four New Alleles at the W1 Locus Associated with Flower Color in Soybean.Dietary flavonoids modulate CYP2C to improve drug oral bioavailability and their qualitative/quantitative structure-activity relationship.Oxidation of Acenaphthene and Acenaphthylene by Human Cytochrome P450 Enzymes.Disease chemopreventive effects and molecular mechanisms of hydroxylated polymethoxyflavones.Cancer chemoprevention through dietary flavonoids: what's limiting?Management of Benign Prostatic Hyperplasia: Could Dietary Polyphenols Be an Alternative to Existing Therapies?Flavonoids and Naphthoflavonoids: Wider Roles in the Modulation of Cytochrome P450 Family 1 Enzymes.Structure–function relationships of inhibition of mosquito cytochrome P450 enzymes by flavonoids of Andrographis paniculata.Rooibos flavonoids inhibit the activity of key adrenal steroidogenic enzymes, modulating steroid hormone levels in H295R cells.Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date.Ethynylflavones, highly potent, and selective inhibitors of cytochrome P450 1A1.Development of flavone propargyl ethers as potent and selective inhibitors of cytochrome P450 enzymes 1A1 and 1A2.QSAR models of cytochrome P450 enzyme 1A2 inhibitors using CoMFA, CoMSIA and HQSAR.Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6.Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS.Effects of Vernonia cinerea Compounds on Drug-metabolizing Cytochrome P450s in Human Liver Microsomes.Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2',5'-Tetrachlorobiphenyl.Identification of CYP1B1-specific candidate inhibitors using combination of in silico screening, integrated knowledge-based filtering, and molecular dynamics simulations."Drugs on oxygen": an update and perspective on the role of cytochrome P450 testing in pharmacology.Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities.Galangin, a dietary flavonol inhibits tumor initiation during experimental pulmonary tumorigenesis by modulating xenobiotic enzymes and antioxidant status.Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.Relationships of Echium plantagineum L. bee pollen, dietary flavonoids and their colonic metabolites with cytochrome P450 enzymes and oxidative stress

P2860

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P2860

Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives

http://www.wikidata.org/entity/Q42023392

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2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Structure-function relationshi ...... A4 by 33 flavonoid derivatives

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Structure-function relationshi ...... A4 by 33 flavonoid derivatives

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type

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Structure-function relationshi ...... A4 by 33 flavonoid derivatives

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Structure-function relationshi ...... A4 by 33 flavonoid derivatives

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Structure-function relationshi ...... A4 by 33 flavonoid derivatives

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Structure-function relationshi ...... A4 by 33 flavonoid derivatives

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P1433

Chemical Research in Toxicology

P1476

Structure-function relationshi ...... A4 by 33 flavonoid derivatives

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P2093

F Peter Guengerich

http://www.w3.org/2001/XMLSchema#string

Katsuhiro Tanaka

http://www.w3.org/2001/XMLSchema#string

Martha V Martin

http://www.w3.org/2001/XMLSchema#string

Maryam K Foroozesh

http://www.w3.org/2001/XMLSchema#string

Masayuki Komori

http://www.w3.org/2001/XMLSchema#string

Norie Murayama

http://www.w3.org/2001/XMLSchema#string

Shigeo Takenaka

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Tsutomu Shimada

http://www.w3.org/2001/XMLSchema#string

P2860

Protein measurement with the Folin phenol reagent

Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2

Recombinant enzymes overexpressed in bacteria show broad catalytic specificity of human cytochrome P450 2W1 and limited activity of human cytochrome P450 2S1

Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity

Mechanism of CYP2C9 inhibition by flavones and flavonols

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution.

Inhibition of extrahepatic human cytochromes P450 1A1 and 1B1 by metabolism of isoflavones found in Trifolium pratense (red clover).

Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450.

Bioavailable flavonoids: cytochrome P450-mediated metabolism of methoxyflavones.

P304

1921-1935

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scholarly article

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10.1021/TX100286D

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P433

12

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P478

23

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P50

Hiroshi Yamazaki

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2010-12-01T00:00:00Z

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47697948

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21053930

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3072440

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