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The genome of the blood fluke Schistosoma mansoniThe NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell lineComputational electrophysiology: the molecular dynamics of ion channel permeation and selectivity in atomistic detailThe hitchhiker's guide to the voltage-gated sodium channel galaxyCalcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapiesThe sodium leak channel, NALCN, in health and diseaseDistinct BOLD fMRI Responses of Capsaicin-Induced Thermal Sensation Reveal Pain-Related Brain Activation in Nonhuman PrimatesNovel screening techniques for ion channel targeting drugsSelection of inhibitor-resistant viral potassium channels identifies a selectivity filter site that affects barium and amantadine blockIdentification and analysis of cation channel homologues in human pathogenic fungiCysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm functionPeptidomimetic Star Polymers for Targeting Biological Ion ChannelsUsing flow technologies to direct the synthesis and assembly of materials in solution.Probing peptide and protein insertion in a biomimetic S-layer supported lipid membrane platformLigand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophoreProfiling diverse compounds by flux- and electrophysiology-based primary screens for inhibition of human Ether-à-go-go related gene potassium channels.A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAA receptors.Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cellsStructural interactions of a voltage sensor toxin with lipid membranes.Pharmacogenomics of cardiovascular complications in diabetes and obesity.Palmitoylation influences the function and pharmacology of sodium channels.Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery.Molecular variability elicits a tunable switch with discrete neuromodulatory response phenotypes.Deconstructing voltage sensor function and pharmacology in sodium channels.Calcium-permeable ion channels in the kidney.Antibody-guided photoablation of voltage-gated potassium currentsInhibition of TRPV1 channels by a naturally occurring omega-9 fatty acid reduces pain and itch.On the role of water density fluctuations in the inhibition of a proton channelIon channels as novel therapeutic targets in the treatment of pain.Introduction to membrane proteins.Intrinsically disordered proteins and novel strategies for drug discovery.Ion channels in postnatal neurogenesis: potential targets for brain repair.TREK-king the blood-brain-barrier.PIP2 regulation of KCNQ channels: biophysical and molecular mechanisms for lipid modulation of voltage-dependent gating.Mutational consequences of aberrant ion channels in neurological disorders.Discovery of functional antibodies targeting ion channels.Role of ion channels in regulating Ca²⁺ homeostasis during the interplay between immune and cancer cells.Interactions of natural polyamines with mammalian proteins.Microfluidic platform for reproducible self-assembly of chemically communicating droplet networks with predesigned number and type of the communicating compartments.New Trends in Cancer Therapy: Targeting Ion Channels and Transporters.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Ion channels as drug targets: the next GPCRs.
@en
Ion channels as drug targets: the next GPCRs.
@nl
type
label
Ion channels as drug targets: the next GPCRs.
@en
Ion channels as drug targets: the next GPCRs.
@nl
prefLabel
Ion channels as drug targets: the next GPCRs.
@en
Ion channels as drug targets: the next GPCRs.
@nl
P2093
P2860
P356
P1476
Ion channels as drug targets: the next GPCRs.
@en
P2093
Birgit T Priest
Gregory J Kaczorowski
Maria L Garcia
Owen B McManus
P2860
P304
P356
10.1085/JGP.200709946
P577
2008-04-14T00:00:00Z