Blockers of the delayed-rectifier potassium current in pancreatic beta-cells enhance glucose-dependent insulin secretion. - Wikidata - awgldk - TriplyDB

Blockers of the delayed-rectifier potassium current in pancreatic beta-cells enhance glucose-dependent insulin secretion.

Blockers of the delayed-rectifier potassium current in pancreatic beta-cells enhance glucose-dependent insulin secretion.

http://www.wikidata.org/entity/Q34506023

about

Solution structure of GxTX-1E, a high-affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channels Portability of paddle motif function and pharmacology in voltage sensors Interactions between lipids and voltage sensor paddles detected with tarantula toxins Kv5, Kv6, Kv8, and Kv9 subunits: No simple silent bystanders Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans Action potentials and insulin secretion: new insights into the role of Kv channels.Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion Single particle image reconstruction of the human recombinant Kv2.1 channel.Oxidation of KCNB1 K(+) channels in central nervous system and beyond Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells Tarantula toxins interacting with voltage sensors in potassium channels.Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels.Solution structure of kurtoxin: a gating modifier selective for Cav3 voltage-gated Ca(2+) channels A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.Distinct Cell- and Layer-Specific Expression Patterns and Independent Regulation of Kv2 Channel Subtypes in Cortical Pyramidal Neurons Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons.Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells.Opening the shaker K+ channel with hanatoxin.The effect of "Teucrium polium L." extracts on insulin release from in situ isolated perfused rat pancreas in a newly modified isolation method: the role of Ca2+ and K+ channels.Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice Deconstructing voltage sensor function and pharmacology in sodium channels.Roles of specific Kv channel types in repolarization of the action potential in genetically identified subclasses of pyramidal neurons in mouse neocortex Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion.A model of action potentials and fast Ca2+ dynamics in pancreatic beta-cells Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons.Ion channel drug discovery: challenges and future directions.Anoctamin 1 (Ano1) is required for glucose-induced membrane potential oscillations and insulin secretion by murine β-cells.Isolation and characterization of SsmTx-I, a Specific Kv2.1 blocker from the venom of the centipede Scolopendra Subspinipes Mutilans L. Koch.Cardiotoxin-I: an unexpectedly potent insulinotropic agent.De novo expression of Kv6.3 contributes to changes in vascular smooth muscle cell excitability in a hypertensive mice strain.Relationship and mechanism of Kv2.1 expression to ADH secretion in rats with heart failure.Ion channels and pain: important steps towards validating a new therapeutic target for neuropathic pain.Ion channels as drug targets: the next GPCRs.Block of Kv1.7 potassium currents increases glucose-stimulated insulin secretion.BK channels mediate a novel ionic mechanism that regulates glucose-dependent electrical activity and insulin secretion in mouse pancreatic β-cells.Physiological roles of Kv2 channels in entorhinal cortex layer II stellate cells revealed by Guangxitoxin-1E.Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy.

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P2860

Blockers of the delayed-rectifier potassium current in pancreatic beta-cells enhance glucose-dependent insulin secretion.

http://www.wikidata.org/entity/Q34506023

description

2006 nî lūn-bûn

@nan

2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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type

label

Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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prefLabel

Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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DIABETES.55.04.06.DB05-0788

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Blockers of the delayed-rectif ...... e-dependent insulin secretion.

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Birgit T Priest

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Chinweze Ahaghotu

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Denise Wunderler

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Gregory J Kaczorowski

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James Herrington

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John T Mehl

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Kristin Raphaelli

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Manuel Sanchez

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Maria L Garcia

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Martin G Kohler

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1034-1042

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scholarly article

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10.2337/DIABETES.55.04.06.DB05-0788

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4

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2006-04-01T00:00:00Z

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7210837

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16567526

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