Modeling colon adenocarcinomas in vitro a 3D co-culture system induces cancer-relevant pathways upon tumor cell and stromal fibroblast interaction.
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The gastrointestinal tumor microenvironmentAssay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid CulturesColon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling.Modeling tumor microenvironments in vitro.The dominant role of IL-8 as an angiogenic driver in a three-dimensional physiological tumor construct for drug testing.Gene expression profiles of the NCI-60 human tumor cell lines define molecular interaction networks governing cell migration processesAn HTS-compatible 3D colony formation assay to identify tumor-specific chemotherapeutics.Spherical cancer models in tumor biology.IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction.High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFκB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts.Dissecting characteristics and dynamics of differentially expressed proteins during multistage carcinogenesis of human colorectal cancer.Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification.Biomaterials and emerging anticancer therapeutics: engineering the microenvironment.Scaffold-Free Coculture Spheroids of Human Colonic Adenocarcinoma Cells and Normal Colonic Fibroblasts Promote Tumorigenicity in Nude Mice.Engineering a High-Throughput 3-D In Vitro Glioblastoma Model.A novel tissue engineered three-dimensional in vitro colorectal cancer model.Liquid-based three-dimensional tumor models for cancer research and drug discovery.Mesenchymal stem cells in the colorectal tumor microenvironment: recent progress and implications.Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.Homogeneous pancreatic cancer spheroids mimic growth pattern of circulating tumor cell clusters and macrometastases: displaying heterogeneity and crater-like structure on inner layer.Real-time monitoring of cisplatin cytotoxicity on three-dimensional spheroid tumor cells.The third dimension: new developments in cell culture models for colorectal research.Progress towards understanding heterotypic interactions in multi-culture models of breast cancer.Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs.Three-dimensional co-culture of hepatic progenitor cells and mesenchymal stem cells in vitro and in vivo.Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia.S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells.Heralding a new paradigm in 3D tumor modeling.The Resazurin Reduction Assay Can Distinguish Cytotoxic from Cytostatic Compounds in Spheroid Screening Assays.In vitro ovarian cancer model based on three-dimensional agarose hydrogel.PDMS well platform for culturing millimeter-size tumor spheroids.Anti-Cancer Drug Validation: the Contribution of Tissue Engineered Models.3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing.Evaporation-based microfluidic production of oil-free cell-containing hydrogel particlesOrganotypic three-dimensional cancer cell cultures mirror drug responses in vivo: lessons learned from the inhibition of EGFR signaling.Roles of Tumor Microenvironment in Hepatocelluar Carcinoma.Biomaterials-Based Approaches to Tumor Spheroid and Organoid Modeling.Three-Dimensional Tissue Models and Available Probes for Multi-Parametric Live Cell Microscopy: A Brief Overview.Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms.Anticancer Applications of Nanostructured Silica-Based Materials Functionalized with Titanocene Derivatives: Induction of Cell Death Mechanism through TNFR1 Modulation.
P2860
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P2860
Modeling colon adenocarcinomas in vitro a 3D co-culture system induces cancer-relevant pathways upon tumor cell and stromal fibroblast interaction.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Modeling colon adenocarcinomas ...... tromal fibroblast interaction.
@en
Modeling colon adenocarcinomas ...... tromal fibroblast interaction.
@nl
type
label
Modeling colon adenocarcinomas ...... tromal fibroblast interaction.
@en
Modeling colon adenocarcinomas ...... tromal fibroblast interaction.
@nl
prefLabel
Modeling colon adenocarcinomas ...... tromal fibroblast interaction.
@en
Modeling colon adenocarcinomas ...... tromal fibroblast interaction.
@nl
P2093
P2860
P1476
Modeling colon adenocarcinomas ...... tromal fibroblast interaction.
@en
P2093
Christian Haslinger
Christian Rupp
Christina Puri
Dontscho Kerjaschki
Elisabeth Wieser
Norbert Schweifer
Pilar Garin-Chesa
P2860
P304
P356
10.1016/J.AJPATH.2011.03.015
P407
P577
2011-04-30T00:00:00Z