Autophosphorylation of the Fes tyrosine kinase. Evidence for an intermolecular mechanism involving two kinase domain tyrosine residues.
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A point mutation in the N-terminal coiled-coil domain releases c-Fes tyrosine kinase activity and survival signaling in myeloid leukemia cellsClosing in on the biological functions of Fps/Fes and FerFES kinases are required for oncogenic FLT3 signalingSpatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scatteringThe human c-Fes tyrosine kinase binds tubulin and microtubules through separate domains and promotes microtubule assemblyCo-expression with BCR induces activation of the FES tyrosine kinase and phosphorylation of specific N-terminal BCR tyrosine residuesTransformation of myeloid leukemia cells to cytokine independence by Bcr-Abl is suppressed by kinase-defective HckSwitches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination systemKinome analysis of receptor-induced phosphorylation in human natural killer cellsActivation of STAT3 by the Src family kinase Hck requires a functional SH3 domain.Interaction of the N-methyl-D-aspartic acid receptor NR2D subunit with the c-Abl tyrosine kinase.The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase.Downregulation of the c-Fes protein-tyrosine kinase inhibits the proliferation of human renal carcinoma cells.Phosphorylation of B-Myb regulates its transactivation potential and DNA binding.Regulation of c-Fes tyrosine kinase and biological activities by N-terminal coiled-coil oligomerization domains.Enhanced endotoxin sensitivity in fps/fes-null mice with minimal defects in hematopoietic homeostasis.Activated Fes protein tyrosine kinase induces terminal macrophage differentiation of myeloid progenitors (U937 cells) and activation of the transcription factor PU.1.Bimolecular fluorescence complementation demonstrates that the c-Fes protein-tyrosine kinase forms constitutive oligomers in living cells.TSLP signaling network revealed by SILAC-based phosphoproteomicsDownregulation of Fes inhibits VEGF-A-induced chemotaxis and capillary-like morphogenesis by cultured endothelial cells.Identification of three crucial histidine residues (His115, His132 and His297) in porcine deoxyribonuclease II.A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer.The nonreceptor protein-tyrosine kinase c-Fes is involved in fibroblast growth factor-2-induced chemotaxis of murine brain capillary endothelial cells.Activation of STAT3 by the c-Fes protein-tyrosine kinase.Proteolytic processing of porcine deoxyribonuclease II occurs in lysosomes but is not required for enzyme activation.Oligomerization of the Fes tyrosine kinase. Evidence for a coiled-coil domain in the unique N-terminal region.Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle.Chemical genetics identifies c-Src as an activator of primitive ectoderm formation in murine embryonic stem cells.Requirement of the coiled-coil domains of p92(c-Fes) for nuclear localization in myeloid cells upon induction of differentiation.Disruption of coiled-coil domains in Fer protein-tyrosine kinase abolishes trimerization but not kinase activation.Interdomain interaction reconstitutes the functionality of PknA, a eukaryotic type Ser/Thr kinase from Mycobacterium tuberculosis.
P2860
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P2860
Autophosphorylation of the Fes tyrosine kinase. Evidence for an intermolecular mechanism involving two kinase domain tyrosine residues.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Autophosphorylation of the Fes ...... nase domain tyrosine residues.
@en
Autophosphorylation of the Fes ...... nase domain tyrosine residues.
@nl
type
label
Autophosphorylation of the Fes ...... nase domain tyrosine residues.
@en
Autophosphorylation of the Fes ...... nase domain tyrosine residues.
@nl
prefLabel
Autophosphorylation of the Fes ...... nase domain tyrosine residues.
@en
Autophosphorylation of the Fes ...... nase domain tyrosine residues.
@nl
P2093
P2860
P356
P1476
Autophosphorylation of the Fes ...... nase domain tyrosine residues.
@en
P2093
P2860
P304
17519-17525
P356
10.1074/JBC.271.29.17519
P407
P577
1996-07-01T00:00:00Z