An echistatin C-terminal peptide activates GPIIbIIIa binding to fibrinogen, fibronectin, vitronectin and collagen type I and type IV.
about
Conformation and concerted dynamics of the integrin-binding site and the C-terminal region of echistatin revealed by homonuclear NMRThe disulphide bond pattern of bitistatin, a disintegrin isolated from the venom of the viper Bitis arietans.Differential recognition of snake venom proteins expressing specific Arg-Gly-Asp (RGD) sequence motifs by wild-type and variant integrin alphaIIbbeta3: further evidence for distinct sites of RGD ligand recognition exhibiting negative allosteryInteraction of disintegrins with the alpha IIb beta 3 receptor on resting and activated human platelets.Preferential antagonism of the interactions of the integrin alpha IIb beta 3 with immobilized glycoprotein ligands by snake-venom RGD (Arg-Gly-Asp) proteins. Evidence supporting a functional role for the amino acid residues flanking the tripeptide RDetermination of the structure of two novel echistatin variants and comparison of the ability of echistatin variants to inhibit aggregation of platelets from different species.Immunological characterization of eristostatin and echistatin binding sites on alpha IIb beta 3 and alpha V beta 3 integrins.Structure-activity studies of the s-echistatin inhibition of bone resorption.Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin.The "linker" region (amino acids 38-47) of the disintegrin elegantin is a novel inhibitory domain of integrin alpha5beta1-dependent cell adhesion on fibronectin: evidence for the negative regulation of fibronectin synergy site biological activity.Substitutions of proline 42 to alanine and methionine 46 to asparagine around the RGD domain of the neurotoxin dendroaspin alter its preferential antagonism to that resembling the disintegrin elegantin.
P2860
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P2860
An echistatin C-terminal peptide activates GPIIbIIIa binding to fibrinogen, fibronectin, vitronectin and collagen type I and type IV.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
An echistatin C-terminal pepti ...... d collagen type I and type IV.
@en
An echistatin C-terminal pepti ...... d collagen type I and type IV.
@nl
type
label
An echistatin C-terminal pepti ...... d collagen type I and type IV.
@en
An echistatin C-terminal pepti ...... d collagen type I and type IV.
@nl
prefLabel
An echistatin C-terminal pepti ...... d collagen type I and type IV.
@en
An echistatin C-terminal pepti ...... d collagen type I and type IV.
@nl
P2093
P2860
P356
P1433
P1476
An echistatin C-terminal pepti ...... d collagen type I and type IV.
@en
P2093
P2860
P304
P356
10.1042/BJ2930263
P407
P478
293 ( Pt 1)
P577
1993-07-01T00:00:00Z