Protein pUL128 of human cytomegalovirus is necessary for monocyte infection and blocking of migration.
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Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complexVirion Glycoprotein-Mediated Immune Evasion by Human Cytomegalovirus: a Sticky Virus Makes a Slick GetawayHuman cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner.PDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway.The HCMV gH/gL/UL128-131 complex triggers the specific cellular activation required for efficient viral internalization into target monocytes.The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.The latency-associated UL138 gene product of human cytomegalovirus sensitizes cells to tumor necrosis factor alpha (TNF-alpha) signaling by upregulating TNF-alpha receptor 1 cell surface expression.A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism.Human cytomegalovirus glycoprotein gO complexes with gH/gL, promoting interference with viral entry into human fibroblasts but not entry into epithelial cells.Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread.HCMV-encoded UL128 enhances TNF-α and IL-6 expression and promotes PBMC proliferation through the MAPK/ERK pathway in vitro.Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism.The US16 gene of human cytomegalovirus is required for efficient viral infection of endothelial and epithelial cells.A Broad-Spectrum Chemokine-Binding Protein of Bovine Papular Stomatitis Virus Inhibits Neutrophil and Monocyte Infiltration in Inflammatory and Wound Models of Mouse Skin.Human cytomegalovirus induction of a unique signalsome during viral entry into monocytes mediates distinct functional changes: a strategy for viral disseminationCytomegalovirus CC chemokine promotes immune cell migration.A cytomegalovirus DNA vaccine induces antibodies that block viral entry into fibroblasts and epithelial cells.The Human Cytomegalovirus UL116 Gene Encodes an Envelope Glycoprotein Forming a Complex with gH Independently from gLRepair of a Mutation Disrupting the Guinea Pig Cytomegalovirus Pentameric Complex Acquired during Fibroblast Passage Restores Pathogenesis in Immune-Suppressed Guinea Pigs and in the Context of Congenital Infection.Impact of sequence variation in the UL128 locus on production of human cytomegalovirus in fibroblast and epithelial cellsHuman cytomegalovirus entry into cells.HCMV reprogramming of infected monocyte survival and differentiation: a Goldilocks phenomenon.HCMV infection of human trophoblast progenitor cells of the placenta is neutralized by a human monoclonal antibody to glycoprotein B and not by antibodies to the pentamer complex.Diverse immune evasion strategies by human cytomegalovirus.Interplay between human cytomegalovirus and intrinsic/innate host responses: a complex bidirectional relationship.Functional annotation of human cytomegalovirus gene products: an update.The pathogenesis of human cytomegalovirus.Principles for studying in vivo attenuation of virus mutants: defining the role of the cytomegalovirus gH/gL/gO complex as a paradigm.Human cytomegalovirus: taking the strain.Genetic Stability of Bacterial Artificial Chromosome-Derived Human Cytomegalovirus during Culture In Vitro.Recombinant HCMV UL128 expression and functional identification of PBMC-attracting activity in vitro.Chemokines encoded by herpesviruses.Cytomegalovirus UL128 homolog mutants that form a pentameric complex produce virus with impaired epithelial and trophoblast cell tropism and altered pathogenicity in the guinea pig.Two glycosaminoglycan-binding domains of the mouse cytomegalovirus-encoded chemokine MCK-2 are critical for oligomerization of the full-length protein.Cytomegalovirus Virions Shed in Urine Have a Reversible Block to Epithelial Cell Entry and Are Highly Resistant to Antibody Neutralization.Host protein Snapin interacts with human cytomegalovirus pUL130 and affects viral DNA replication.Tetraspanin CD151 Promotes Initial Events in Human Cytomegalovirus Infection.Human cytomegalovirus infection of langerhans-type dendritic cells does not require the presence of the gH/gL/UL128-131A complex and is blocked after nuclear deposition of viral genomes in immature cells.Cytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+ CD4- dendritic cells.Mck2-dependent infection of alveolar macrophages promotes replication of MCMV in nodular inflammatory foci of the neonatal lung.
P2860
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P2860
Protein pUL128 of human cytomegalovirus is necessary for monocyte infection and blocking of migration.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Protein pUL128 of human cytome ...... ion and blocking of migration.
@en
Protein pUL128 of human cytome ...... ion and blocking of migration.
@nl
type
label
Protein pUL128 of human cytome ...... ion and blocking of migration.
@en
Protein pUL128 of human cytome ...... ion and blocking of migration.
@nl
prefLabel
Protein pUL128 of human cytome ...... ion and blocking of migration.
@en
Protein pUL128 of human cytome ...... ion and blocking of migration.
@nl
P2093
P2860
P356
P1433
P1476
Protein pUL128 of human cytome ...... ion and blocking of migration.
@en
P2093
Andrea Gallina
Giada Frascaroli
Marco Patrone
Paul Walther
Sarah Straschewski
Thomas Mertens
P2860
P304
P356
10.1128/JVI.02100-10
P407
P577
2011-03-02T00:00:00Z