Comparative study of the binding pockets of mammalian proprotein convertases and its implications for the design of specific small molecule inhibitors.

Comparative study of the binding pockets of mammalian proprotein convertases and its implications for the design of specific small molecule inhibitors.

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http://www.wikidata.org/entity/Q42082859
Computational prediction of furin cleavage sites by a hybrid method and understanding mechanism underlying diseasesAnalysis of cathepsin and furin proteolytic enzymes involved in viral fusion protein activation in cells of the bat reservoir host.Polyphenols as therapeutic molecules in Alzheimer's disease through modulating amyloid pathways.Proprotein convertase inhibition: Paralyzing the cell's master switches.On the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications.FurinDB: A database of 20-residue furin cleavage site motifs, substrates and their associated drugs.A novel eight amino acid insertion contributes to the hemagglutinin cleavability and the virulence of a highly pathogenic avian influenza A (H7N3) virus in mice.Proprotein convertases process and thereby inactivate formylglycine-generating enzyme.The Multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cells.The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.
P2860

Comparative study of the binding pockets of mammalian proprotein convertases and its implications for the design of specific small molecule inhibitors.

Item
http://www.wikidata.org/entity/Q42082859
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2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-my
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2010年學術文章
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name
Comparative study of the bindi ...... fic small molecule inhibitors.
@en
Comparative study of the bindi ...... fic small molecule inhibitors.
@nl
type
label
Comparative study of the bindi ...... fic small molecule inhibitors.
@en
Comparative study of the bindi ...... fic small molecule inhibitors.
@nl
prefLabel
Comparative study of the bindi ...... fic small molecule inhibitors.
@en
Comparative study of the bindi ...... fic small molecule inhibitors.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Comparative study of the bindi ...... fic small molecule inhibitors.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932