Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. - Wikidata - awgldk - TriplyDB

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

http://www.wikidata.org/entity/Q42095035

about

Pathological and protective roles of glia in chronic pain Spinal interleukin-10 therapy to treat peripheral neuropathic pain Intrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion.Emerging targets in neuroinflammation-driven chronic pain PEGylation of interleukin-10 for the mitigation of enhanced pain states.Mesoporous silica-supported lipid bilayers (protocells) for DNA cargo delivery to the spinal cord.Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain.Monocytes/Macrophages control resolution of transient inflammatory pain.Pathological pain and the neuroimmune interface.Efficacy of some non-conventional herbal medications (sulforaphane, tanshinone IIA, and tetramethylpyrazine) in inducing neuroprotection in comparison with interleukin-10 after spinal cord injury: A meta-analysis.(+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats.Caudal granular insular cortex is sufficient and necessary for the long-term maintenance of allodynic behavior in the rat attributable to mononeuropathy Current gene therapy using viral vectors for chronic pain Release of plasmid DNA-encoding IL-10 from PLGA microparticles facilitates long-term reversal of neuropathic pain following a single intrathecal administration Glia in pathological pain: a role for fractalkine A human trial of HSV-mediated gene transfer for the treatment of chronic pain.Interferon alpha inhibits spinal cord synaptic and nociceptive transmission via neuronal-glial interactions.Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain.Cytokine and chemokine regulation of sensory neuron function.Long-term control of neuropathic pain in a non-viral gene therapy paradigm.Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes The therapeutic potential of interleukin-10 in neuroimmune diseases.Central nervous system delivery of large molecules: challenges and new frontiers for intrathecally administered therapeutics.Gene therapy for the treatment of chronic peripheral nervous system pain.Neuropathic pain and cytokines: current perspectives.Destination Brain: the Past, Present, and Future of Therapeutic Gene Delivery.The RS504393 Influences the Level of Nociceptive Factors and Enhances Opioid Analgesic Potency in Neuropathic Rats.Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia.The administration of BDNF and GDNF to the brain via PLGA microparticles patterned within a degradable PEG-based hydrogel: Protein distribution and the glial response.High cerebrospinal fluid levels of interleukin-10 attained by AAV in dogs.Systemic administration of an alpha-7 nicotinic acetylcholine agonist reverses neuropathic pain in male Sprague Dawley rats.Effects of spinal non-viral interleukin-10 gene therapy formulated with d-mannose in neuropathic interleukin-10 deficient mice: Behavioral characterization, mRNA and protein analysis in pain relevant tissues.Inhibition of neuropathic hyperalgesia by intrathecal bone marrow stromal cells is associated with alteration of multiple soluble factors in cerebrospinal fluid.IL-10 and IL-1β mediate neuropathic-pain like behavior in the ventrolateral orbital cortex.Interleukin-10 of red nucleus plays anti-allodynia effect in neuropathic pain rats with spared nerve injury.Divergent roles of immune cells and their mediators in pain.Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors.Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity

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P2860

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

http://www.wikidata.org/entity/Q42095035

description

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name

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

@en

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

@nl

type

label

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

@en

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

@nl

prefLabel

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

@en

Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

@nl

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S1740925X07000488

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Neuron Glia Biology

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Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.

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Erin D Milligan

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Evan M Sloane

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John H Mahoney

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Leslie A Leinwand

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Melissa J Mahoney

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Ryan G Soderquist

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Stephanie M Malone

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Stephen J Langer

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Steven F Maier

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Travis S Hughes

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P2860

Interleukin-10 and the interleukin-10 receptor

Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10

Alternative activation of macrophages

Expression and regulation of interleukin-10 and interleukin-10 receptor in rat astroglial and microglial cells

Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain

Innate immunity: the virtues of a nonclonal system of recognition

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120.

Evaluation of particle uptake in human blood monocyte-derived cells in vitro. Does phagocytosis activity of dendritic cells measure up with macrophages?

Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity.

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293-308

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scholarly article

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10.1017/S1740925X07000488

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4

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2

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Linda R. Watkins

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2006-11-01T00:00:00Z

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5768564

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18079973

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neuropathic pain

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2133369

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